TREX1 Antikörper (Middle Region)

Produktnummer ABIN3043537

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TREX1 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TREX1 Antikörper (Middle Region) (ABIN3043537)

Target: TREX1 (three Prime Repair Exonuclease 1 (TREX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TREX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TREX1 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: Anti-TREX1 Antibody

Sequenz: DDNLANLLLA FLRRQPQPWC LVAHNGDRYD

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse sequence by four amino acids.

Produktmerkmale: Anti-TREX1 Antibody. Tested in WB applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human TREX1, different from the related mouse sequence by four amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TREX1

Target: TREX1 (three Prime Repair Exonuclease 1 (TREX1))

Andere Bezeichnung: TREX1

Hintergrund:

Background: Three prime repair exonuclease 1 is an enzyme that in humans is encoded by the TREX1 gene. This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants.

Gene Full Name: three prime repair exonuclease 1

Molekulargewicht: 33 kDa

Gen-ID: 11277

UniProt: Q9NSU2

Pathways: Apoptose