HRPT2 Antikörper (AA 119-520)

Produktnummer ABIN3043535

Produktdetails anti-HRPT2 Antikörper

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Bindungsspezifität: AA 119-520

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HRPT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Parafibromin(CDC73) detection. Tested with WB in Human.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Parafibromin(CDC73) detection. Tested with WB in Human.
Gene Name: cell division cycle 73
Protein Name: Parafibromin

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human HRPT2 recombinant protein (Position: Q119-R520). Human HRPT2 shares 100% and 99.8% amino acid (aa) sequence identity with mouse and rat HRPT2, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu HRPT2

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Andere Bezeichnung: CDC73 (CDC73 Produkte)

Synonyme: C1orf28 antikoerper, HPTJT antikoerper, HRPT2 antikoerper, HYX antikoerper, 8430414L16Rik antikoerper, BC027756 antikoerper, C130030P16Rik antikoerper, C81219 antikoerper, Hrpt2 antikoerper, hrpt2 antikoerper, zgc:63956 antikoerper, MGC108428 antikoerper, cdc73 antikoerper, LOC100222932 antikoerper, cell division cycle 73 antikoerper, cell division cycle 73, Paf1/RNA polymerase II complex component antikoerper, cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) antikoerper, parafibromin antikoerper, cell division cycle 73 S homeolog antikoerper, CDC73 antikoerper, Cdc73 antikoerper, cdc73 antikoerper, Tsp_03925 antikoerper, Tsp_04052 antikoerper, Tsp_04125 antikoerper, cdc73.S antikoerper

Hintergrund: Cell division cycle 73, also known as HRPT2, is a protein which in humans is encoded by the CDC73 gene. This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. And this protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.

Synonyms: C1orf28 antibody|CDC 73 antibody|Cdc73 antibody|CDC73_HUMAN antibody|Cell division cycle 73 antibody|Cell division cycle 73 Paf1/RNA polymerase II complex component homolog antibody| Cell division cycle protein 73 homolog antibody|FLJ23316 antibody|HPT JT antibody|HPTJT antibody|HRPT 2 antibody|Hyperparathyroidism 2 (with jaw tumor) antibody| Hyperparathyroidism 2 antibody|Hyperparathyroidism 2 protein antibody|HYX antibody| Parafibromin antibody

Gen-ID: 79577

UniProt: Q6P1J9

Pathways: Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance