BIRC7 Antikörper (AA 87-298)

Produktnummer ABIN3043512

Dieses Anti-BIRC7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BIRC7 in WB und ELISA. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für BIRC7 Antikörper (AA 87-298) (ABIN3043512)

Target: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BIRC7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-BIRC7 Antikörper

Bindungsspezifität: AA 87-298

Verwendungszweck: Anti-Livin/BIRC7 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-Livin/BIRC7 Antibody (ABIN3043512). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human Livin recombinant protein (Position: E87-S298). Human Livin shares 69.8% amino acid (aa) sequence identity with mouse Livin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, -
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: BIRC7 baculoviral IAP repeat-containing 7 (livin)". 2. Kasof GM, Gomes BC (May 2001). "Livin, a novel inhibitor of apoptosis protein family member". J Biol Chem 276 (5): 3238-46. 3. Lin JH, Deng G, Huang Q, Morser J (Feb 2001). "KIAP, a novel member of the inhibitor of apoptosis protein family". Biochem Biophys Res Commun 279 (3): 820-31.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Referenzen für anti-BIRC7 Antikörper (ABIN3043512)

Guo, Gao, Zhang, Jing, Liu, Shi, Zhai, Jing, Du: "Expression and clinical significance of livin protein in hepatocellular carcinoma." in: Disease markers, Vol. 35, Issue 5, pp. 489-96, (2014) (PubMed).

Details zu BIRC7

Target: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Andere Bezeichnung: BIRC7

Hintergrund:

Synonyms: Baculoviral IAP repeat-containing protein 7,6.3.2.-,Kidney inhibitor of apoptosis protein,KIAP,Livin,Melanoma inhibitor of apoptosis protein,ML-IAP,RING finger protein 50,Baculoviral IAP repeat-containing protein 7 30 kDa subunit,Truncated livin,p30-Livin,tLivin,BIRC7,KIAP, LIVIN, MLIAP, RNF50,UNQ5800/PRO19607/PRO21344,

Tissue Specificity: Isoform 1 and isoform 2 are expressed at very low levels or not detectable in most adult tissues. Detected in adult heart, placenta, lung, lymph node, spleen and ovary, and in several carcinoma cell lines. Isoform 2 is detected in fetal kidney, heart and spleen, and at lower levels in adult brain, skeletal muscle and peripheral blood leukocytes.

Background: Baculoviral IAP repeat-containing protein 7 is a protein that in humans is encoded by the BIRC7 gene. This protein is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) and a RING finger motif. Its gene is mapped to 20q13.3. It has got 280- and 298- amino acids. The protein is highly expressed in melanomas while lowly expressed in some lymphomas, fetal kidney, fetal liver, testis and thymus. BIRC7 plays a vital role in blocking apoptosis induced.

Sequence Similarities: Belongs to the IAP family.

Molekulargewicht: 33 kDa

Gen-ID: 79444