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Annexin A3 Antikörper (Middle Region)

ANXA3 Reaktivität: Human, Maus, Ratte WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3043501
  • Target Alle Annexin A3 (ANXA3) Antikörper anzeigen
    Annexin A3 (ANXA3)
    Bindungsspezifität
    • 12
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 153-184, Middle Region
    Reaktivität
    • 74
    • 19
    • 16
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 61
    • 19
    Kaninchen
    Klonalität
    • 63
    • 16
    Polyklonal
    Konjugat
    • 50
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser Annexin A3 Antikörper ist unkonjugiert
    Applikation
    • 57
    • 26
    • 22
    • 9
    • 9
    • 7
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Verwendungszweck
    Anti-Annexin A3/ANXA3 Antibody Picoband®
    Sequenz
    RKALLTLADG RRDESLKVDE HLAKQDAQIL YK
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins
    Produktmerkmale
    Anti-Annexin A3/ANXA3 Antibody Picoband® (ABIN3043501). Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence in the middle region of human Annexin A3, different from the related mouse sequence by one amino acid, and from the related rat sequence by three amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product ANXA3 Primärantikörper
  • Applikationshinweise
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    Western blot, 0.1-0.5 μg/mL
    Immunocytochemistry , 0.5-1 μg/mL
    1. Bianchi C, et al. Primary cell cultures from human renal cortex and renal-cell carcinoma evidence a differential expression of two spliced isoforms of Annexin A3. Am J Pathol, 2010 Apr. 2. Jung EJ, et al. Decreased annexin A3 expression correlates with tumor progression in papillary thyroid cancer. Proteomics Clin Appl, 2010 May. 3. Yan X, et al. Increased expression of annexin A3 is a mechanism of platinum resistance in ovarian cancer. Cancer Res, 2010 Feb 15.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target
    Annexin A3 (ANXA3)
    Andere Bezeichnung
    ANXA3 (ANXA3 Produkte)
    Hintergrund

    Synonyms: Annexin A3,35-alpha calcimedin,Annexin III,Annexin-3,Inositol 1,2-cyclic phosphate 2-phosphohydrolase,Lipocortin III,Placental anticoagulant protein III,PAP-III,ANXA3,ANX3,

    Tissue Specificity: Expressed in all tissues tested including brain, heart, kidney, liver, lung, muscle, ovary, skin, spleen and thymus. .

    Background: Annexin A3 is a protein that in humans is encoded by the Annexin A3 gene. The Annexin A3 gene contains 13 exons and spans 58 kb of genomic DNA. The Annexin A3 gene is mapped to 4q21. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.

    Sequence Similarities: Belongs to the annexin family.

    Molekulargewicht
    36 kDa
    Gen-ID
    306
    UniProt
    P12429
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