rala Antikörper (C-Term)

Produktnummer ABIN3043449

Produktdetails anti-rala Antikörper

Target: rala (Ras-related Protein Ral-A (rala))

Bindungsspezifität: AA 165-203, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser rala Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Ras-related protein Ral-A(RALA) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: DKVFFDLMRE IRARKMEDSK EKNGKKKRKS LAKRIRERC

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Ras-related protein Ral-A(RALA) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: v-ral simian leukemia viral oncogene homolog A (ras related)
Protein Name: Ras-related protein Ral-A

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human RALA (165-203aa DKVFFDLMREIRARKMEDSKEKNGKKKRKSLAKRIRERC), identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu rala

Target: rala (Ras-related Protein Ral-A (rala))

Andere Bezeichnung: RALA (rala Produkte)

Synonyme: 3010001O15Rik antikoerper, AW322615 antikoerper, Ral antikoerper, Rasl1 antikoerper, RAL antikoerper, v-ral simian leukemia viral oncogene A (ras related) antikoerper, RAS like proto-oncogene A antikoerper, Rala antikoerper, RALA antikoerper

Hintergrund: Ras-related protein Ral-A (RalA) is a protein that in humans is encoded by the RALA gene on chromosome 7. This protein is one of two isoforms of the Ral protein, the other being RalB, and part of the Ras GTPase family. As a Ras GTPase, RalA functions as a molecular switch that becomes active when bound to GTP and inactive when bound to GDP. It can be activated by RalGEFs and, in turn, activate effectors in signal transduction pathways leading to biological outcomes. Additionally, Ral proteins have been associated with the progression of several cancers, including bladder cancer and prostate cancer. While the above functions appear to be shared between the two Ral isoforms, their differential subcellular localizations result in their differing involvement in certain biological processes. In particular, RalA is more involved in anchorage-independent cell growth, vesicle trafficking, and cytoskeletal organization. Moreover, RalA specifically interacts with Exo84 and Sec5 to regulate transport of membrane proteins in polarized epithelial cells and GLUT4 to the plasma membrane, as well as mitochondrial fission for cell division.

Synonyms: MGC48949 antibody|Ral a antibody|Ral A protein antibody|RAL antibody|RALA antibody|RALA_HUMAN antibody|Ras family small GTP binding protein RALA antibody|RAS like protein A antibody|Ras related protein RalA antibody|Ras-related protein Ral-A antibody|v ral simian leukemia viral oncogene homolog A (ras related) antibody|v ral simian leukemia viral oncogene homolog A antibody

Gen-ID: 5898

UniProt: P11233

Pathways: Neurotrophin Signalübertragung, SARS-CoV-2 Protein Interaktom