POT1 Antikörper (N-Term)

Produktnummer ABIN3043444

Produktdetails anti-POT1 Antikörper

Target: POT1 (Protection of Telomeres 1 (POT1))

Bindungsspezifität: AA 195-234, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Protection of telomeres protein 1(POT1) detection. Tested with WB in Human.

Sequenz: RVLIQDLVLE GDLSHIHRLQ NLTIDILVYD NHVHVARSLK

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Protection of telomeres protein 1(POT1) detection. Tested with WB in Human.
Gene Name: protection of telomeres 1
Protein Name: Protection of telomeres protein 1

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human POT1 (195-234aa RVLIQDLVLEGDLSHIHRLQNLTIDILVYDNHVHVARSLK), different from the related mouse sequence by eleven amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu POT1

Target: POT1 (Protection of Telomeres 1 (POT1))

Andere Bezeichnung: POT1 (POT1 Produkte)

Synonyme: HPOT1 antikoerper, POT1 antikoerper, DKFZp469P1825 antikoerper, pot1 antikoerper, 1500031H18Rik antikoerper, AI851169 antikoerper, Pot1 antikoerper, Pot1a antikoerper, protection of telomeres 1 antikoerper, protection of telomeres 1 L homeolog antikoerper, protection of telomeres 1A antikoerper, POT1 antikoerper, pot1.L antikoerper, Pot1a antikoerper, Pot1 antikoerper

Hintergrund: Protection of telomeres protein 1 is a protein that in humans is encoded by the POT1 gene. This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.

Synonyms: DKFZP586D211 antibody|hPot 1 antibody|hPot1 antibody|POT 1 antibody|POT1 antibody|POT1 like telomere end-binding protein antibody|POT1 protection of telomeres 1 homolog antibody|POT1-like telomere end-binding protein antibody|POTE1_HUMAN antibody|Protection of telomeres 1 antibody|Protection of telomeres 1 homolog (S. pombe) antibody|Protection of telomeres protein 1 antibody

Gen-ID: 25913

Pathways: Zellzyklus, Telomere Maintenance