Sp3 Antikörper (C-Term)

Produktnummer ABIN3043350

Dieses Anti-Sp3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Sp3 in WB und IHC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Sp3 Antikörper (C-Term) (ABIN3043350)

Target: Sp3 (Sp3 Transcription Factor (Sp3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sp3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Sp3 Antikörper

Bindungsspezifität: AA 569-599, C-Term

Verwendungszweck: Anti-SP3 Antibody Picoband®

Sequenz: NTNDLTHLRV QVVDEEGDQQ HQEGKRLRRV A

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-SP3 Antibody Picoband® (ABIN3043350). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SP3, identical to the related mouse sequence.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: SP3 Sp3 transcription factor". 2. Sun, Jian-Min, Chen Hou Yu, Moniwa Mariko, Litchfield David W, Seto Edward, Davie James R (September 2002). "The transcriptional repressor Sp3 is associated with CK2-phosphorylated histone deacetylase 2". J. Biol. Chem.(United States) 277 (39): 35783-6.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu Sp3

Target: Sp3 (Sp3 Transcription Factor (Sp3))

Andere Bezeichnung: SP3

Hintergrund:

Synonyms: Transcription factor Sp3,SPR-2,SP3,

Tissue Specificity: Ubiquitously expressed.

Background: Sp3 transcription factor, also known as SP3, refers to both a protein and the gene it is encoded by. This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. And this protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13.

Sequence Similarities: Belongs to the Sp1 C2H2-type zinc-finger protein family.

Molekulargewicht: 82 kDa

Gen-ID: 6670

UniProt: Q02447