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Sp3 Antikörper (C-Term)

Sp3 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3043350
  • Target Alle Sp3 Antikörper anzeigen
    Sp3 (Sp3 Transcription Factor (Sp3))
    Bindungsspezifität
    • 14
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 569-599, C-Term
    Reaktivität
    • 38
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    Human, Maus, Ratte
    Wirt
    • 34
    • 4
    Kaninchen
    Klonalität
    • 34
    • 4
    Polyklonal
    Konjugat
    • 17
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Sp3 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 19
    • 12
    • 12
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Verwendungszweck
    Anti-SP3 Antibody Picoband®
    Sequenz
    NTNDLTHLRV QVVDEEGDQQ HQEGKRLRRV A
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins
    Produktmerkmale
    Anti-SP3 Antibody Picoband® (ABIN3043350). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human SP3, identical to the related mouse sequence.
    Isotyp
    IgG
    Top Product
    Discover our top product Sp3 Primärantikörper
  • Applikationshinweise
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. "Entrez Gene: SP3 Sp3 transcription factor". 2. Sun, Jian-Min, Chen Hou Yu, Moniwa Mariko, Litchfield David W, Seto Edward, Davie James R (September 2002). "The transcriptional repressor Sp3 is associated with CK2-phosphorylated histone deacetylase 2". J. Biol. Chem.(United States) 277 (39): 35783-6.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target
    Sp3 (Sp3 Transcription Factor (Sp3))
    Andere Bezeichnung
    SP3 (Sp3 Produkte)
    Hintergrund

    Synonyms: Transcription factor Sp3,SPR-2,SP3,

    Tissue Specificity: Ubiquitously expressed.

    Background: Sp3 transcription factor, also known as SP3, refers to both a protein and the gene it is encoded by. This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. And this protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13.

    Sequence Similarities: Belongs to the Sp1 C2H2-type zinc-finger protein family.

    Molekulargewicht
    82 kDa
    Gen-ID
    6670
    UniProt
    Q02447
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