SFRP2 Antikörper (AA 104-295)

Produktnummer ABIN3043333

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SFRP2 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SFRP2 Antikörper (AA 104-295) (ABIN3043333)

Target: SFRP2 (Secreted Frizzled-Related Protein 2 (SFRP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SFRP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SFRP2 Antikörper

Bindungsspezifität: AA 104-295

Verwendungszweck: Anti-SFRP2 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-SFRP2 Antibody Picoband® (ABIN3043333). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SFRP2 recombinant protein (Position: L104-C295). Human SFRP2?shares?99%?amino?acid?(aa)?sequence?identity?with mouse SFRP2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, -
ELISA, 0.1-0.5 μg/mL, -
1. Hao XW, et al. Epigenetic inactivation of secreted frizzled-related protein 2 in esophageal squamous cell carcinoma. World J Gastroenterol, 2012 Feb 14. 2. O'Hurley G, et al. The role of secreted frizzled-related protein 2 expression in prostate cancer. Histopathology, 2011 Dec. 3. Sui C, et al. Variation risks of SFRP2 hypermethylation between precancerous disease and colorectal cancer. Tumour Biol, 2014 Oct.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu SFRP2

Target: SFRP2 (Secreted Frizzled-Related Protein 2 (SFRP2))

Andere Bezeichnung: SFRP2

Hintergrund:

Synonyms: Secreted frizzled-related protein 2,FRP-2,sFRP-2,Secreted apoptosis-related protein 1,SARP-1,SFRP2,FRP2, SARP1,FKSG12, UNQ361/PRO697,

Tissue Specificity: Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon. .

Background: SFRP2 is also known as FRP-2, SARP1 or SDF-5. It is Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon. This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.?

Sequence Similarities: Belongs to the secreted frizzled-related protein (sFRP) family.

Molekulargewicht: 33 kDa

Gen-ID: 6423

Pathways: WNT Signalweg, Tube Formation, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Positive Regulation of fat Cell Differentiation