Interferon gamma Antikörper (C-Term)

Produktnummer ABIN3043185

Dieser Anti-Interferon gamma Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von Interferon gamma in WB. Geeignet für Human. Dieses Primary Antibody wurde in 6+ Publikationen zitiert.

Kurzübersicht für Interferon gamma Antikörper (C-Term) (ABIN3043185)

Target: Interferon gamma (IFNG)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Interferon gamma Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Interferon gamma Antikörper

Bindungsspezifität: AA 151-166, C-Term

Verwendungszweck: Anti-Interferon gamma/IFNG Antibody

Sequenz: KRKRSQMLFR GRRASQ

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-Interferon gamma/IFNG Antibody (ABIN3043185). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human IFN gamma.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Interferon gamma Antikörper (ABIN3043185)

Chen, Zhao, Zhang, Yang, Zhao, Zhang, Yan, Pan, Li, Zhang, Li: "Tangshen Formula Attenuates Colonic Structure Remodeling in Type 2 Diabetic Rats." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2017, pp. 4064156, (2017) (PubMed).

Li, Wu, Hang, Zhang, Li: "Women with recurrent spontaneous abortion have decreased 25(OH) vitamin D and VDR at the fetal-maternal interface." in: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, Vol. 50, Issue 11, pp. e6527, (2017) (PubMed).

Liu, Tan, Hu, Wu, Wang, Liu, Tang: "Somatostatin Improved B Cells Mature in Macaques during Intestinal Ischemia-Reperfusion." in: PLoS ONE, Vol. 10, Issue 7, pp. e0133692, (2016) (PubMed).

Ma, Chen, Bo, Lu, Zhang: "Protective effect of carnosine after chronic cerebral hypoperfusion possibly through suppressing astrocyte activation." in: American journal of translational research, Vol. 7, Issue 12, pp. 2706-15, (2016) (PubMed).

Yan, Wang, Liang, Fu, Guo: "HPV16L1-attenuated Shigella recombinant vaccine induced strong vaginal and systemic immune responses in guinea pig model." in: Human vaccines & immunotherapeutics, Vol. 10, Issue 12, pp. 3491-8, (2015) (PubMed).

Liu, Tan, Hu, Wu, Wang, Tang: "Somatostatin inhibits the production of interferon-γ by intestinal epithelial cells during intestinal ischemia-reperfusion in macaques." in: Digestive diseases and sciences, Vol. 59, Issue 10, pp. 2423-32, (2014) (PubMed).

Details zu Interferon gamma

Target: Interferon gamma (IFNG)

Andere Bezeichnung: IFNG

Hintergrund:

Synonyms: Interferon gamma,IFN-gamma,Immune interferon,IFNG,

Tissue Specificity: Released primarily from activated T lymphocytes.

Background: Interferon-gamma (IFN-gamma) is an inflammatory cytokine that has been implicated in the development of fibrosis in inflamed tissues. The production of < a href="https://www.bosterbio.com/anti-interferon-gamma-picoband-trade-antibody-a00393-1-boster.html" style="color:#EA8D28">IFN-gamma, which is under genetic control, can influence the development of fibrosis in lung allografts. IFN-gamma is also produced by natural killer (NK) cells and most prominently by CD8 cytotoxic T cells, and is vital for the control of microbial pathogens. Interferon gamma is believed to be crucial for host defence against many infections. Genetically determined variability in IFN-gamma and expression might be important for the development of tuberculosis. IFN-gamma activates human macrophage oxidative metabolism and antimicrobial activity. In addition to having antiviral activity, IFN-gamma has important immunoregulatory functions. IFN-gamma plays an important role in the control of neointima proliferation.

Sequence Similarities: Belongs to the type II (or gamma) interferon family.

Molekulargewicht: 19 kDa

UniProt: P01579

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagie