IL2RG Antikörper (Middle Region)

Produktnummer ABIN3043145

Der Kaninchen Polyklonal anti-IL2RG Antikörper wird verwendet zum Nachweis von IL2RG in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für IL2RG Antikörper (Middle Region) (ABIN3043145)

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL2RG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IL2RG Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: Anti-IL2 Receptor gamma/IL2RG Antibody

Sequenz: HYWYKNSDND KVQKC

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-IL2 Receptor gamma/IL2RG Antibody. Tested in WB applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human IL2 Receptor gamma.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu IL2RG

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Andere Bezeichnung: IL2RG

Hintergrund:

Background: IL2RG (INTERLEUKIN 2 RECEPTOR, GAMMA),also known as Common gamma chain or CD132, is a cytokine receptor sub-unit that is common to the receptor complexes for at least six different interleukin receptors:IL-2, IL-4, IL-7, IL-9, IL-15 and interleukin-21 receptor. IL2RG is a member of the type I cytokine receptor family expressed on most lymphocyte (white blood cell) populations, and its gene is found on the X-chromosome of mammals. By fluorescence in situ hybridization and PCR amplification of somatic cell hybrid DNAs, The IL2RG gene is mapped to Xq13.1. The IL2RG gene contains 8 exons and spans approximately 4.2 kb. And the gamma chain is an indispensable component of the functional IL2 receptor. Lymphocytes expressing the common gamma chain can form functional receptors for these cytokine proteins, which transmit signals from one cell to another and programs of cellular differentiation. The sharing of the gamma subunit by several receptors explains why humans and mice that lack IL2 entirely show milder symptoms than those with IL2RG deficiency.

Gene Full Name: interleukin 2 receptor subunit gamma

Sequence Similarities: Belongs to the type I cytokine receptor family. Type 5 subfamily.

Molekulargewicht: 75 kDa

Gen-ID: 3561

UniProt: P31785

Pathways: JAK-STAT Signalweg, Growth Factor Binding