Kallikrein 5 Antikörper (C-Term)

Produktnummer ABIN3043138

Produktdetails anti-Kallikrein 5 Antikörper

Target: Kallikrein 5 (KLK5)

Bindungsspezifität: AA 278-293, C-Term

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Kallikrein 1-related peptidase b5(KLK5) detection. Tested with WB, IHC-P in Mouse,Rat.

Sequenz: NLCEFVKWIK DTMNSN

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Kallikrein 1-related peptidase b5(KLK5) detection. Tested with WB, IHC-P in Mouse,Rat.
Gene Name: kallikrein-related peptidase 5
Protein Name: Kallikrein 1-related peptidase b5

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Kallikrein 5(278-293aa NLCEFVKWIKDTMNSN), different from the related rat sequence by three amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Kallikrein 5

Target: Kallikrein 5 (KLK5)

Andere Bezeichnung: KLK5 (KLK5 Produkte)

Synonyme: KLK-L2 antikoerper, KLKL2 antikoerper, SCTE antikoerper, 1110030O19Rik antikoerper, KAL antikoerper, KALA antikoerper, Klk1 antikoerper, Klk5 antikoerper, RATKALA antikoerper, kallikrein related peptidase 5 antikoerper, kallikrein related-peptidase 5 antikoerper, kallikrein 5-like antikoerper, KLK5 antikoerper, Klk5 antikoerper, Klk5l antikoerper

Hintergrund: KLK5(Kallikrein-related peptidase 5), formerly known as stratum corneum tryptic enzyme(SCTE) or KLKL2, is a serine protease expressed in the epidermis. The KLK5 gene is one of the fifteen kallikrein subfamily members which is located on 19q13.41. KLK5 has been suggested to regulate cell shedding in conjunction with KLK7 and KLK14, given its ability to degrade proteins which form the extracellular component of cell junctions in the stratum corneum. The KLK5 gene contains 5 coding exons spanning 9.3. KLK5 expression is upregulated in a breast cancer cell line in the presence of estrogens and progestins and is associated with more aggressive forms of epithelial ovarian carcinoma.

Synonyms: HK5 antibody|Kallikrein 5 antibody|Kallikrein L2 antibody|Kallikrein Like 2 antibody|Kallikrein like protein 2 antibody|Kallikrein related peptidase 5 antibody|Kallikrein-5 antibody|Kallikrein-like protein 2 antibody|Kallikrein5 antibody|KLK 5 antibody|KLK L2 antibody|KLK-L2 antibody|KLK5 antibody|KLK5_HUMAN antibody|KLKL 2 antibody|KLKL2 antibody|SCTE antibody|Stratum Corneum Tryptic Enzyme antibody|UNQ570/PRO1132 antibody

UniProt: Q9D140

Pathways: Komplementsystem, Regulation of G-Protein Coupled Receptor Protein Signaling