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Kallikrein 1 Antikörper (C-Term)

KLK1 Reaktivität: Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3043136
  • Target Alle Kallikrein 1 (KLK1) Antikörper anzeigen
    Kallikrein 1 (KLK1)
    Bindungsspezifität
    • 16
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 243-261, C-Term
    Reaktivität
    • 56
    • 24
    • 22
    Ratte
    Wirt
    • 60
    • 6
    • 2
    Kaninchen
    Klonalität
    • 65
    • 3
    Polyklonal
    Konjugat
    • 31
    • 10
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Kallikrein 1 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 25
    • 24
    • 18
    • 13
    • 13
    • 11
    • 8
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Kallikrein-1(Ngfg) detection. Tested with WB, IHC-P in Rat.
    Sequenz
    YTKLIKFTPW IKEVMKENP
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Kallikrein-1(Ngfg) detection. Tested with WB, IHC-P in Rat.
    Gene Name: kallikrein 1
    Protein Name: Kallikrein-1
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of rat Kallikrein 1(243-261aa YTKLIKFTPWIKEVMKENP).
    Isotyp
    IgG
    Top Product
    Discover our top product KLK1 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Konservierungsmittel
    Thimerosal (Merthiolate), Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Haltbarkeit
    12 months
  • Zhang, Xu, Zhao, Chen: "Genistein improves inflammatory response and colonic function through NF-κB signal in DSS-induced colonic injury." in: Oncotarget, Vol. 8, Issue 37, pp. 61385-61392, (2017) (PubMed).

    Lin, Lin, Chung, Vonderfecht, Camden, Flodby, Borok, Limesand, Mizushima, Ann: "Dynamic involvement of ATG5 in cellular stress responses." in: Cell death & disease, Vol. 5, pp. e1478, (2014) (PubMed).

  • Target
    Kallikrein 1 (KLK1)
    Andere Bezeichnung
    KLK1 (KLK1 Produkte)
    Synonyme
    KLKR antikoerper, Klk6 antikoerper, hK1 antikoerper, klkr antikoerper, kallikrein antikoerper, 0610007D04Rik antikoerper, Kal antikoerper, Klk1b6 antikoerper, mGk-6 antikoerper, kallikrein 1 antikoerper, kallikrein 1 L homeolog antikoerper, KLK1 antikoerper, klk1.L antikoerper, LOC100101620 antikoerper, Klk1 antikoerper
    Hintergrund
    KLK1(KALLIKREIN 1), also called KLKR, is a protein that in humans is encoded by the KLK1 gene. KLK1 is a member of the peptidase S1 family. KLK1 is a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The KLK1 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and its exact cytogenetic location is 19q13.33. The KLK1 gene contains 5 coding exons. And KLK1 is the most centromeric gene in the cluster. Mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.

    Synonyms: Glandular kallikrein 1 antibody|hK 1 antibody|hK1 antibody|Kallikrein serine protease 1 antibody|Kallikrein-1 antibody|Kidney/pancreas/salivary gland kallikrein antibody|Klk 6 antibody|KLK1 antibody|KLK1_HUMAN antibody|Klk6 antibody|KLKR antibody|Tissue kallikrein antibody
    UniProt
    P00758
    Pathways
    Komplementsystem
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