IL-13 Antikörper (C-Term)

Produktnummer ABIN3043089

Zitiert in 6+ Publikationen. Der Kaninchen Polyklonal anti-IL-13 Antikörper (ABIN3043089) detektiert spezifisch IL-13 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IL-13 Antikörper (C-Term) (ABIN3043089)

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IL-13 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Anti-Interleukin-13 IL13 Antibody

Sequenz: HLKKLFREGR FN

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-Interleukin-13 IL13 Antibody. Tested in WB applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human IL-13.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-IL-13 Antikörper (ABIN3043089)

Liu, Wang, Cao, Liu, Zou, Li, Yang, Jiao: "Number 2 Feibi Recipe Reduces PM2.5-Induced Lung Injury in Rats." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 3674145, (2018) (PubMed).

Zhu, Li, Wu, Lu, You, Li, Li, Yang, Duan: "Acute exposure of ozone induced pulmonary injury and the protective role of vitamin E through the Nrf2 pathway in Balb/c mice." in: Toxicology research, Vol. 5, Issue 1, pp. 268-277, (2018) (PubMed).

Li, Zhang, Qin, Bi, Liu, Li, Cai, Ma, Chan, Xie, Guan: "CD68 and interleukin 13, prospective immune markers for esophageal squamous cell carcinoma prognosis prediction." in: Oncotarget, Vol. 7, Issue 13, pp. 15525-38, (2017) (PubMed).

Wang, Liang, Wang, Zhu, Gong, Zhang, Li, Xia: "Th17 down-regulation is involved in reduced progression of schistosomiasis fibrosis in ICOSL KO mice." in: PLoS neglected tropical diseases, Vol. 9, Issue 1, pp. e0003434, (2016) (PubMed).

Long, Chen, Zhao, Rafaels, Mathias, Liang, Potee, Campbell, Zhang, Gao, Georas, Vercelli, Beaty, Ruczinski, Mathias, Barnes, Chen: "An IL-13 promoter polymorphism associated with liver fibrosis in patients with Schistosoma japonicum." in: PLoS ONE, Vol. 10, Issue 8, pp. e0135360, (2016) (PubMed).

Li, Li, Zuo, Ke, Yan, Wen, Zhang, Yang: "T-helper type-2 contact hypersensitivity of Balb/c mice aggravated by dibutyl phthalate via long-term dermal exposure." in: PLoS ONE, Vol. 9, Issue 2, pp. e87887, (2014) (PubMed).

Details zu IL-13

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Andere Bezeichnung: IL13

Hintergrund:

Background: IL-13, Interleukin 13, is a protein that in humans is encoded by the IL-13 gene. IL-13 is cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, that is an important mediator of allergic inflammation and disease. The IL-13 gene is mapped to 5q23-q31. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Ralpha) and at least one of two known IL-13-specific binding chains. IL-13 acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.

Gene Full Name: interleukin 13

Sequence Similarities: Belongs to the IL-4/IL-13 family.

Molekulargewicht: 58 kDa

Gen-ID: 3596

UniProt: P35225

Pathways: JAK-STAT Signalweg, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport