Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Neurotrophin 3 Antikörper (Middle Region)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Neurotrophin 3 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte und wurde in 1 Publikation erwähnt.
Produktnummer ABIN3043024

Kurzübersicht für Neurotrophin 3 Antikörper (Middle Region) (ABIN3043024)

Target

Alle Neurotrophin 3 (NTF3) Antikörper anzeigen
Neurotrophin 3 (NTF3)

Reaktivität

  • 80
  • 46
  • 40
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 69
  • 14
  • 4
  • 3
  • 2
Kaninchen

Klonalität

  • 78
  • 14
Polyklonal

Konjugat

  • 60
  • 6
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Neurotrophin 3 Antikörper ist unkonjugiert

Applikation

  • 76
  • 38
  • 24
  • 23
  • 23
  • 13
  • 13
  • 7
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 15
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 174-189, Middle Region

    Verwendungszweck

    Anti-Neurotrophin 3/NTF3 Antibody Picoband®

    Sequenz

    TVLGEIKTGN SPVKQY

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Neurotrophin 3/NTF3 Antibody (ABIN3043024). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence in the middle region of human Neurotrophin 3, identical to the related rat and mouse sequences.

    Isotyp

    IgG
  • Applikationshinweise

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Human, Mouse
    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. Jones, K. R., Reichardt, L. F. : Molecular cloning of a human gene that is a member of the nerve growth factor family. Proc. Nat. Acad. Sci. 87: 8060-8064, 1990. 2. Rosenthal A., Goeddel D.V., Nguyen T., Lewis M., Shih A., Laramee G.R., Nikolics K., Winslow J.W.,"Primary structure and biological activity of a novel human neurotrophic factor.",Neuron 4:767-773(1990).

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    Konservierungsmittel

    Thimerosal (Merthiolate), Sodium azide

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Guo, Zeng, Li, Huang, Liu, Li, Ding, Wu, Cai: "Cotransplant of neural stem cells and NT-3 gene modified Schwann cells promote the recovery of transected spinal cord injury." in: Spinal cord, Vol. 45, Issue 1, pp. 15-24, (2007) (PubMed).

  • Target

    Neurotrophin 3 (NTF3)

    Andere Bezeichnung

    NTF3

    Hintergrund

    Synonyms: Neurotrophin-3,NT-3,HDNF,Nerve growth factor 2,NGF-2,Neurotrophic factor,NTF3,

    Tissue Specificity: Brain and peripheral tissues.

    Background: Neurotrophin-3 is a member of a family of neurotrophic factors, that is closely related to both nerve growth factor and brain derived neurotrophic factor. These proteins are involved in the maintenance of the adult nervous system and affect development of neurons in the embryo when it is expressed in human placenta. NT3 deficient mice generated by gene targeting display severe movement defects of the limbs.

    Sequence Similarities: Belongs to the enolase family.

    Molekulargewicht

    47 kDa

    UniProt

    P20783

    Pathways

    RTK Signalweg, Neurotrophin Signalübertragung
Sie sind hier:
Chat with us!