PLTP Antikörper (Middle Region)

Produktnummer ABIN3042820

Produktdetails anti-PLTP Antikörper

Target: PLTP (Phospholipid Transfer Protein (PLTP))

Bindungsspezifität: AA 256-271, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLTP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Verwendungszweck: Anti-Phospholipid transfer protein PLTP Antibody Picoband®

Sequenz: QLQEEERMVY VAFSEF

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-Phospholipid transfer protein PLTP Antibody (ABIN3042820). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human PLTP.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Jiang, X., Bruce, C., Mar, J., Lin, M., Ji, Y., Francone, O. L., Tall, A. R. Targeted mutation of plasma phospholipid transfer protein gene markedly reduces high-absorbance lipoprotein levels. J. Clin. Invest. 103: 907-914, 1999. 2. Spirin, V., Schmidt, S., Pertsemlidis, A., Cooper, R. S., Cohen, J. C., Sunyaev, S. R. Common single-nucleotide polymorphisms act in concert to affect plasma levels of high-absorbance lipoprotein cholesterol. Am. J. Hum. Genet. 81: 1298-1303, 2007. 3. Teslovich, T. M., Musunuru, K., Smith, A. V., Edmondson, A. C., Stylianou, I. M., Koseki, M., Pirruccello, J. P., Ripatti, S., Chasman, D. I., Willer, C. J., Johansen, C. T., Fouchier, S. W., and 197 others. Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466: 707-713, 2010.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PLTP

Target: PLTP (Phospholipid Transfer Protein (PLTP))

Andere Bezeichnung: PLTP (PLTP Produkte)

Hintergrund:

Synonyms: Phospholipid transfer protein,Lipid transfer protein II,PLTP,

Tissue Specificity: Wide tissue distribution. Placenta > pancreas > lung > kidney > heart > liver > skeletal muscle > brain.

Background: Phospholipid transfer protein (PLTP), also known as lipid transfer protein II is a protein that in humans is encoded by the PLTP gene. This gene is mapped to 20q13.12. The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene.

Sequence Similarities: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

Molekulargewicht: 55 kDa

UniProt: P55058

Pathways: Lipid Metabolism