M-CSF/CSF1 Antikörper (AA 33-262)

Produktnummer ABIN3042763

Produktdetails anti-M-CSF/CSF1 Antikörper

Target: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Bindungsspezifität: AA 33-262

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser M-CSF/CSF1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Macrophage colony-stimulating factor 1(CSF1) detection. Tested with IHC-P, ELISA in Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Macrophage colony-stimulating factor 1(CSF1) detection. Tested with IHC-P, ELISA in Mouse,Rat.
Gene Name: colony stimulating factor 1 (macrophage)
Protein Name: Macrophage colony-stimulating factor 1

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived mouse MCSF recombinant protein (Position: K33-E262). Mouse MCSF shares 80.9 % and 88.6% amino acid (aa) sequence identity with human and rat MCSF, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse

Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-M-CSF/CSF1 Antikörper (ABIN3042763)

Pei, Sun, Zhang, Wang, Ren: "Interstitial tumor-associated macrophages combined with tumor-derived colony-stimulating factor-1 and interleukin-6, a novel prognostic biomarker in non-small cell lung cancer." in: The Journal of thoracic and cardiovascular surgery, Vol. 148, Issue 4, pp. 1208-1216.e2, (2015) (PubMed).

Details zu M-CSF/CSF1

Target: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Andere Bezeichnung: CSF1 (CSF1 Produkte)

Synonyme: CSF-1 antikoerper, MCSF antikoerper, C87615 antikoerper, Csfm antikoerper, op antikoerper, csf1-1 antikoerper, zgc:172186 antikoerper, CSF1 antikoerper, csf1-2 antikoerper, zgc:158436 antikoerper, colony stimulating factor 1 antikoerper, colony stimulating factor 1 (macrophage) antikoerper, colony stimulating factor 1a (macrophage) antikoerper, macrophage colony-stimulating factor 1 antikoerper, macrophage colony stimulating factor antikoerper, colony stimulating factor 1b (macrophage) antikoerper, CSF1 antikoerper, Csf1 antikoerper, csf1a antikoerper, LOC396599 antikoerper, LOC100860895 antikoerper, csf1b antikoerper

Hintergrund: M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival ofmonocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor (CSF1R or M-CSF-R encoded by the c-fms proto-oncogene), M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.

Synonyms: Colony stimulating factor 1 (macrophage) antibody|Colony stimulating factor 1 antibody| Colony stimulating factor macrophage specific antibody|CSF 1 antibody|CSF-1 antibody|CSF1 antibody|CSF1_HUMAN antibody|Csfm antibody|Lanimostim antibody|M CSF antibody|M-CSF antibody|Macrophage Colony Stimulating Factor 1 antibody|Macrophage colony stimulating factor antibody|MCSF antibody|MGC31930 antibody|Processed macrophage colony-stimulating factor 1 antibody

Gen-ID: 12977

UniProt: P07141

Pathways: RTK Signalweg