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CPT1B Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CPT1B in WB, IHC, IF und IHC (fro). Er zeigt eine Reaktivität gegenüber Maus und Ratte.
Produktnummer ABIN3042757

Kurzübersicht für CPT1B Antikörper (N-Term) (ABIN3042757)

Target

Alle CPT1B Antikörper anzeigen
CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))

Reaktivität

  • 60
  • 21
  • 18
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Maus, Ratte

Wirt

  • 59
  • 2
  • 1
Kaninchen

Klonalität

  • 60
  • 2
Polyklonal

Konjugat

  • 29
  • 6
  • 5
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CPT1B Antikörper ist unkonjugiert

Applikation

  • 57
  • 38
  • 23
  • 13
  • 13
  • 7
  • 6
  • 5
  • 5
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 15
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 197-226, N-Term

    Verwendungszweck

    Anti-CPT1B Antibody Picoband®

    Sequenz

    DDEEYYRMEL LAKEFQDKTA PRLQKYLVLK

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-CPT1B Antibody Picoband® (ABIN3042757). Tested in IF, IHC, IHC-F, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the N-terminus of human CPT1B, different from the related mouse sequence by two amino acids, and from the related rat sequence by four amino acids.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
    Immunofluorescence, 5 μg/mL1. Auinger A, Rubin D, Sabandal M, Helwig U, Rüther A, Schreiber S, Foelsch UR, Döring F, Schrezenmeir J. ""A common haplotype of carnitine palmitoyltransferase 1b is associated with the metabolic syndrome"". Br J Nutr, 2013 Mar 14.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))

    Andere Bezeichnung

    CPT1B

    Hintergrund

    Synonyms: Carnitine O-palmitoyltransferase 1, muscle isoform,CPT1-M,2.3.1.21,Carnitine O-palmitoyltransferase I, muscle isoform,CPT I,CPTI-M,Carnitine palmitoyltransferase 1B,Carnitine palmitoyltransferase I-like protein,CPT1B,KIAA1670,

    Tissue Specificity: Strong expression in heart and skeletal muscle. No expression in liver and kidney.

    Background: CPT1B is located on 22q13.33. The protein encoded by this gene, a member of the carnitine/ choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene.

    Sequence Similarities: Belongs to the carnitine/choline acetyltransferase family.

    Molekulargewicht

    88 kDa

    Gen-ID

    1375

    UniProt

    Q92523

    Pathways

    AMPK Signaling, Monocarboxylic Acid Catabolic Process
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