CPT1B Antikörper (N-Term)

Produktnummer ABIN3042757

Produktdetails anti-CPT1B Antikörper

Target: CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))

Bindungsspezifität: AA 197-226, N-Term

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CPT1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Verwendungszweck: Anti-CPT1B Antibody Picoband®

Sequenz: DDEEYYRMEL LAKEFQDKTA PRLQKYLVLK

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-CPT1B Antibody Picoband® (ABIN3042757). Tested in IF, IHC, IHC-F, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human CPT1B, different from the related mouse sequence by two amino acids, and from the related rat sequence by four amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunofluorescence, 5 μg/mL1. Auinger A, Rubin D, Sabandal M, Helwig U, Rüther A, Schreiber S, Foelsch UR, Döring F, Schrezenmeir J. ""A common haplotype of carnitine palmitoyltransferase 1b is associated with the metabolic syndrome"". Br J Nutr, 2013 Mar 14.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu CPT1B

Target: CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))

Andere Bezeichnung: CPT1B (CPT1B Produkte)

Hintergrund:

Synonyms: Carnitine O-palmitoyltransferase 1, muscle isoform,CPT1-M,2.3.1.21,Carnitine O-palmitoyltransferase I, muscle isoform,CPT I,CPTI-M,Carnitine palmitoyltransferase 1B,Carnitine palmitoyltransferase I-like protein,CPT1B,KIAA1670,

Tissue Specificity: Strong expression in heart and skeletal muscle. No expression in liver and kidney.

Background: CPT1B is located on 22q13.33. The protein encoded by this gene, a member of the carnitine/ choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene.

Sequence Similarities: Belongs to the carnitine/choline acetyltransferase family.

Molekulargewicht: 88 kDa

Gen-ID: 1375

UniProt: Q92523

Pathways: AMPK Signaling, Monocarboxylic Acid Catabolic Process