IL-13 Antikörper (AA 22-131)

Produktnummer ABIN3042737

Produktdetails anti-IL-13 Antikörper

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Bindungsspezifität: AA 22-131

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-13 Antikörper ist unkonjugiert

Applikation: ELISA

Verwendungszweck: Rabbit IgG polyclonal antibody for Interleukin-13(IL13) detection. Tested with ELISA in Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Interleukin-13(IL13) detection. Tested with ELISA in Rat.
Gene Name: interleukin 13
Protein Name: Interleukin-13

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived rat IL-13 recombinant protein (Position: P22-H131). Rat IL-13 shares 62% and 76% amino acid (aa) sequence identity with human and mouse IL-13, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat

Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-IL-13 Antikörper (ABIN3042737)

Li, Li, Zuo, Ke, Yan, Wen, Zhang, Yang: "T-helper type-2 contact hypersensitivity of Balb/c mice aggravated by dibutyl phthalate via long-term dermal exposure." in: PLoS ONE, Vol. 9, Issue 2, pp. e87887, (2014) (PubMed).

Details zu IL-13

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Andere Bezeichnung: IL13 (IL13 Produkte)

Synonyme: IL13 antikoerper, IL-13 antikoerper, P600 antikoerper, Il-13 antikoerper, L13 antikoerper, interleukin 13 antikoerper, IL13 antikoerper, Il13 antikoerper

Hintergrund: IL-13, Interleukin 13, is a protein that in humans is encoded by the IL-13 gene. IL-13 is a kind of cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, which is an important mediator of allergic inflammation and disease. The IL-13 gene is mapped to 5q23-q31. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. This gene acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.

Synonyms: Allergic rhinitis antibody|ALRH antibody|BHR1 antibody|Bronchial hyperresponsiveness 1 (bronchial asthma) antibody|IL 13 antibody|IL-13 antibody|Il13 antibody|IL13_HUMAN antibody|Interleukin 13 antibody|Interleukin-13 antibody|MGC116786 antibody|MGC116788 antibody|MGC116789 antibody|NC30 antibody|P600 antibody

Gen-ID: 116553

UniProt: P42203

Pathways: JAK-STAT Signalweg, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport