SOCS2 Antikörper (AA 96-198)

Produktnummer ABIN3042487

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch SOCS2 in WB. Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für SOCS2 Antikörper (AA 96-198) (ABIN3042487)

Target: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOCS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SOCS2 Antikörper

Bindungsspezifität: AA 96-198

Verwendungszweck: Anti-SOCS2 Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-SOCS2 Antibody (ABIN3042487). Tested in WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SOCS2 recombinant protein (Position: R96-V198). Human SOCS2 shares 96.1% and 95.1% amino acid (aa) sequence identity with mouse and rat SOCS2, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Rat

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu SOCS2

Target: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Andere Bezeichnung: SOCS2

Hintergrund:

Synonyms: Suppressor of cytokine signaling 2,SOCS-2,Cytokine-inducible SH2 protein 2,CIS-2,STAT-induced STAT inhibitor 2,SSI-2,SOCS2,CIS2, SSI2, STATI2,

Tissue Specificity: High expression in heart, placenta, lung, kidney and prostate.

Background: Suppressor of cytokine signaling 2 is a protein that in humans is encoded by the SOCS2 gene. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signalling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon-gamma (IFN-gamma). The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor 1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. By cytogenetic and radiation hybrid mapping, Yandava et al. (1999) mapped the SOCS2 gene to chromosome 12q21.3-q23.

Sequence Similarities: Contains 1 SH2 domain.

Molekulargewicht: 22 kDa

Gen-ID: 8835

UniProt: O14508

Pathways: JAK-STAT Signalweg, Response to Growth Hormone Stimulus