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Kallikrein 4 Antikörper (AA 31-254)

KLK4 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3042476
  • Target Alle Kallikrein 4 (KLK4) Antikörper anzeigen
    Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))
    Bindungsspezifität
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-254
    Reaktivität
    • 24
    • 12
    • 6
    Human
    Wirt
    • 31
    • 6
    Kaninchen
    Klonalität
    • 31
    • 6
    Polyklonal
    Konjugat
    • 23
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Kallikrein 4 Antikörper ist unkonjugiert
    Applikation
    • 29
    • 20
    • 13
    • 12
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Verwendungszweck
    Anti-Kallikrein 4/KLK4 Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins
    Produktmerkmale
    Anti-Kallikrein 4/KLK4 Antibody Picoband® (ABIN3042476). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human Kallikrein 4 recombinant protein (Position: I31-S254).
    Isotyp
    IgG
    Top Product
    Discover our top product KLK4 Primärantikörper
  • Applikationshinweise
    Western blot, 0.1-0.5 μg/mL, Human
    1. Klokk, T. I., Kilander, A., Xi, Z., Waehre, H., Risberg, B., Danielson, H. E., Saatcioglu, F. Kallikrein 4 is a proliferative factor that is overexpressed in prostate cancer. Cancer Res. 67: 5221-5230, 2007. 2. Nelson PS, Gan L, Ferguson C, Moss P, Gelinas R, Hood L, Wang K (March 1999). 3. Simmer JP, Fukae M, Tanabe T, Yamakoshi Y, Uchida T, Xue J, Margolis HC, Shimizu M, DeHart BC, Hu CC, Bartlett JD (June 2000).
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target
    Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))
    Andere Bezeichnung
    KLK4 (KLK4 Produkte)
    Hintergrund

    Synonyms: Kallikrein-4,3.4.21.-,Enamel matrix serine proteinase 1,Kallikrein-like protein 1,KLK-L1,Prostase,Serine protease 17,KLK4,EMSP1, PRSS17, PSTS,

    Tissue Specificity: Expressed in prostate.

    Background: Kallikrein-related peptidase 4, also known as PSTS or EMSP1, is a protein which in humans is encoded by the KLK4 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. In particular, they may serve as biomarkers for both prostate cancer and breast cancer. It has been found that KLK4 is a proliferative factor with effects on gene expression and it may have a role in prostate cancer development and progression.

    Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.

    Molekulargewicht
    27 kDa
    Gen-ID
    9622
    UniProt
    Q9Y5K2
    Pathways
    Komplementsystem
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