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Kallikrein 4 Antikörper (AA 31-254)

Der Kaninchen Polyklonal Anti-Kallikrein 4-Antikörper wurde für WB validiert. Er ist geeignet, Kallikrein 4 in Proben von Human zu detektieren.
Produktnummer ABIN3042476

Kurzübersicht für Kallikrein 4 Antikörper (AA 31-254) (ABIN3042476)

Target

Alle Kallikrein 4 (KLK4) Antikörper anzeigen
Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))

Reaktivität

  • 24
  • 12
  • 6
Human

Wirt

  • 31
  • 6
Kaninchen

Klonalität

  • 31
  • 6
Polyklonal

Konjugat

  • 23
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Kallikrein 4 Antikörper ist unkonjugiert

Applikation

  • 29
  • 20
  • 13
  • 12
  • 7
  • 3
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-254

    Verwendungszweck

    Anti-Kallikrein 4/KLK4 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Kallikrein 4/KLK4 Antibody Picoband® (ABIN3042476). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human Kallikrein 4 recombinant protein (Position: I31-S254).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human
    1. Klokk, T. I., Kilander, A., Xi, Z., Waehre, H., Risberg, B., Danielson, H. E., Saatcioglu, F. Kallikrein 4 is a proliferative factor that is overexpressed in prostate cancer. Cancer Res. 67: 5221-5230, 2007. 2. Nelson PS, Gan L, Ferguson C, Moss P, Gelinas R, Hood L, Wang K (March 1999). 3. Simmer JP, Fukae M, Tanabe T, Yamakoshi Y, Uchida T, Xue J, Margolis HC, Shimizu M, DeHart BC, Hu CC, Bartlett JD (June 2000).

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))

    Andere Bezeichnung

    KLK4

    Hintergrund

    Synonyms: Kallikrein-4,3.4.21.-,Enamel matrix serine proteinase 1,Kallikrein-like protein 1,KLK-L1,Prostase,Serine protease 17,KLK4,EMSP1, PRSS17, PSTS,

    Tissue Specificity: Expressed in prostate.

    Background: Kallikrein-related peptidase 4, also known as PSTS or EMSP1, is a protein which in humans is encoded by the KLK4 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. In particular, they may serve as biomarkers for both prostate cancer and breast cancer. It has been found that KLK4 is a proliferative factor with effects on gene expression and it may have a role in prostate cancer development and progression.

    Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.

    Molekulargewicht

    27 kDa

    Gen-ID

    9622

    UniProt

    Q9Y5K2

    Pathways

    Komplementsystem
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