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FZD1 Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FZD1 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN3042412

Kurzübersicht für FZD1 Antikörper (C-Term) (ABIN3042412)

Target

Alle FZD1 (Fzd1) Antikörper anzeigen
FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

Reaktivität

  • 36
  • 14
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 36
  • 5
  • 3
  • 2
Kaninchen

Klonalität

  • 39
  • 7
Polyklonal

Konjugat

  • 30
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FZD1 Antikörper ist unkonjugiert

Applikation

  • 29
  • 17
  • 16
  • 9
  • 7
  • 7
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 369-400, C-Term

    Verwendungszweck

    Anti-Frizzled homolog 1/FZD1 Antibody Picoband®

    Sequenz

    YIAGFLLEDR VVCNDKFAED GARTVAQG

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Frizzled homolog 1/FZD1 Antibody Picoband® (ABIN3042412). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the C-terminus of human Frizzled homolog 1, identical to the related mouse and rat sequences.

    Isotyp

    IgG
  • Applikationshinweise

    Immunohistochemistry (Paraffin-embedded Section), 0.5-2 μg/mL, Human
    Western blot, 0.1-0.6 μg/mL, Human
    1. "Entrez Gene: FZD1 frizzled homolog 1 (Drosophila)". 2. Gazit A, Yaniv A, Bafico A, Pramila T, Igarashi M, Kitajewski J, Aaronson SA (Oct 1999). "Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response". Oncogene 18(44): 5959-66. 3. Sagara N, Toda G, Hirai M, Terada M, Katoh M (Nov 1998). "Molecular cloning, differential expression, and chromosomal localization of human frizzled-1, frizzled-2, and frizzled-7". Biochemical and Biophysical Research Communications 252 (1): 117-22.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

    Andere Bezeichnung

    FZD1

    Hintergrund

    Synonyms: Frizzled-1,Fz-1,hFz1,FzE1,FZD1,

    Tissue Specificity: Expressed in adult heart, placenta, lung, kidney, pancreas, prostate, and ovary and in fetal lung and kidney.

    Background: Frizzled-1 (Frizzled homolog 1) is a protein that in humans is encoded by the FZD1 gene. Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signalingproteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.

    Sequence Similarities: Belongs to the G-protein coupled receptor Fz/Smo family.

    Molekulargewicht

    71 kDa

    Gen-ID

    8321

    Pathways

    WNT Signalweg, Asymmetric Protein Localization
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