FZD1 Antikörper (C-Term)
Kurzübersicht für FZD1 Antikörper (C-Term) (ABIN3042412)
Target
Alle FZD1 (Fzd1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 369-400, C-Term
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Verwendungszweck
- Anti-Frizzled homolog 1/FZD1 Antibody Picoband®
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Sequenz
- YIAGFLLEDR VVCNDKFAED GARTVAQG
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
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Produktmerkmale
- Anti-Frizzled homolog 1/FZD1 Antibody Picoband® (ABIN3042412). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human Frizzled homolog 1, identical to the related mouse and rat sequences.
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Isotyp
- IgG
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Applikationshinweise
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Immunohistochemistry (Paraffin-embedded Section), 0.5-2 μg/mL, Human
Western blot, 0.1-0.6 μg/mL, Human
1. "Entrez Gene: FZD1 frizzled homolog 1 (Drosophila)". 2. Gazit A, Yaniv A, Bafico A, Pramila T, Igarashi M, Kitajewski J, Aaronson SA (Oct 1999). "Human frizzled 1 interacts with transforming Wnts to transduce a TCF dependent transcriptional response". Oncogene 18(44): 5959-66. 3. Sagara N, Toda G, Hirai M, Terada M, Katoh M (Nov 1998). "Molecular cloning, differential expression, and chromosomal localization of human frizzled-1, frizzled-2, and frizzled-7". Biochemical and Biophysical Research Communications 252 (1): 117-22. -
Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
- 500 μg/mL
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Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))
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Andere Bezeichnung
- FZD1
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Hintergrund
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Synonyms: Frizzled-1,Fz-1,hFz1,FzE1,FZD1,
Tissue Specificity: Expressed in adult heart, placenta, lung, kidney, pancreas, prostate, and ovary and in fetal lung and kidney.
Background: Frizzled-1 (Frizzled homolog 1) is a protein that in humans is encoded by the FZD1 gene. Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signalingproteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.
Sequence Similarities: Belongs to the G-protein coupled receptor Fz/Smo family.
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Molekulargewicht
- 71 kDa
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Gen-ID
- 8321
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Pathways
- WNT Signalweg, Asymmetric Protein Localization
Target
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