FURIN Antikörper (AA 591-794)

Produktnummer ABIN3042409

Produktdetails anti-FURIN Antikörper

Target: FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))

Bindungsspezifität: AA 591-794

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FURIN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Furin(FURIN) detection. Tested with WB in Human.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Furin(FURIN) detection. Tested with WB in Human.
Gene Name: furin (paired basic amino acid cleaving enzyme)
Protein Name: Furin

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Furin recombinant protein (Position: T591-L794). Human Furin shares 88% amino acid (aa) sequence identity with both mouse and rat Furin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Furin is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu FURIN

Target: FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))

Andere Bezeichnung: FURIN (FURIN Produkte)

Synonyme: FURIN antikoerper, furin antikoerper, si:dkey-281a24.5 antikoerper, FUR antikoerper, LOC100220259 antikoerper, PACE antikoerper, spc1 antikoerper, xfurin antikoerper, MGC82710 antikoerper, PCSK3 antikoerper, SPC1 antikoerper, 9130404I01Rik antikoerper, Fur antikoerper, Pcsk3 antikoerper, Pace antikoerper, furin, paired basic amino acid cleaving enzyme antikoerper, furin (paired basic amino acid cleaving enzyme) a antikoerper, furin (paired basic amino acid cleaving enzyme) b antikoerper, furin, paired basic amino acid cleaving enzyme L homeolog antikoerper, furin (paired basic amino acid cleaving enzyme) antikoerper, FURIN antikoerper, furina antikoerper, furinb antikoerper, furin antikoerper, furin.L antikoerper, Furin antikoerper

Hintergrund: Furin(Fur), also known as PACE, is a protein that in humans is encoded by the FURIN gene. The protein encoded by this gene is an enzyme which belongs to the subtilisin-like proprotein convertase family. The Furin gene is located approximately 1 kb upstream of the FES gene on chromosome 15q25-q26. This gene is thought to play a role in tumor progression. Furin is one of the proteases responsible for the proteolytic cleavage of HIV envelope polyprotein precursor gp160 to gp120 and gp41 prior to viral assembly. Furin is enriched in the Golgi apparatus, where it functions to cleave other proteins into their mature/active forms. Expression of furin in T-cells is required for maintenance of peripheral immune tolerance.

Synonyms: Dibasic processing enzyme antibody|Dibasic-processing enzyme antibody|FES upstream region antibody|FUR antibody|FURIN antibody|Furin membrane associated receptor protein antibody|FURIN_HUMAN antibody|PACE antibody|Paired basic amino acid residue cleaving enzyme antibody|Paired basic amino acid residue-cleaving enzyme antibody|PCSK3 antibody|Proprotein convertase subtilisin/kexin type 3 antibody|SPC1 antibody

Gen-ID: 5045

UniProt: P09958

Pathways: Notch Signalweg, Neurotrophin Signalübertragung