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FOXA3 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-FOXA3-Antikörper wurde für WB, IHC, FACS, ICC und IF validiert. Er ist geeignet, FOXA3 in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN3042401

Kurzübersicht für FOXA3 Antikörper (C-Term) (ABIN3042401)

Target

Alle FOXA3 Antikörper anzeigen
FOXA3 (Forkhead Box A3 (FOXA3))

Reaktivität

  • 13
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Human, Maus, Ratte

Wirt

  • 10
  • 3
Kaninchen

Klonalität

  • 12
  • 1
Polyklonal

Konjugat

  • 10
  • 1
  • 1
  • 1
Dieser FOXA3 Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • Bindungsspezifität

    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 291-324, C-Term

    Verwendungszweck

    Anti-FOXA3 Antibody Picoband®

    Sequenz

    ELKLDAPYNF NHPFSINNLM SEQTPAPPKL DVGF

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-FOXA3 Antibody Picoband® (ABIN3042401). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the C-terminus of human FOXA3, different from the related mouse and rat sequences by three amino acids.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human
    Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
    1. "Entrez Gene: forkhead box A3". 2. Mincheva A, Lichter P, Schütz G, Kaestner KH (February 1997). "Assignment of the human genes for hepatocyte nuclear factor 3-alpha, -beta, and -gamma (HNF3A, HNF3B, HNF3G) to 14q12-q13, 20p11, and 19q13.2-q13.4".Genomics 39 (3): 417-9. 3. Navas MA, Vaisse C, Boger S, et al. (2000). "The human HNF-3 genes: cloning, partial sequence and mutation screening in patients with impaired glucose homeostasis.". Hum. Hered. 50 (6): 370-81.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    FOXA3 (Forkhead Box A3 (FOXA3))

    Andere Bezeichnung

    FOXA3

    Hintergrund

    Synonyms: Hepatocyte nuclear factor 3-gamma,HNF-3-gamma,HNF-3G,Fork head-related protein FKH H3,Forkhead box protein A3,Transcription factor 3G,TCF-3G,FOXA3,HNF3G, TCF3G,

    Tissue Specificity: Expressed in erythroleukemia and hepatoma cell lines and in liver and pancreas. Not expressed in any other cell lines or tissues examined. .

    Background: Hepatocyte nuclear factor 3-gamma (HNF-3G), also known as forkhead box protein A3 (FOXA3) or transcription factor 3G (TCF-3G), is a protein that in humans is encoded by the FOXA3 gene. This gene is mapped to 19q13.32. HNF-3G is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. The crystal structure of a similar protein in rat has been resolved.

    Molekulargewicht

    37 kDa

    Gen-ID

    3171

    UniProt

    P55318

    Pathways

    Carbohydrate Homeostasis
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