FGF1 Antikörper (AA 22-146)

Produktnummer ABIN3042389

Produktdetails anti-FGF1 Antikörper

Target: FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

Bindungsspezifität: AA 22-146

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Fibroblast growth factor 1(FGF1) detection. Tested with WB in Human.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Fibroblast growth factor 1(FGF1) detection. Tested with WB in Human.
Gene Name: fibroblast growth factor 1 (acidic)
Protein Name: Fibroblast growth factor 1

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human FGF1 recombinant protein (Position: N22-L146). Human FGF1 shares 97% amino acid (aa) sequence identity with both mouse and rat FGF1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for FGF1 is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-FGF1 Antikörper (ABIN3042389)

Zhang, Wang, Wang, Jiang, Yu, Chong, Fu: "Ferulic acid ameliorates nerve injury induced by cerebral ischemia in rats." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 972-976, (2015) (PubMed).

Zhou, Ren, Zhu, Yan, Wang, Song, Li, Ouyang, Pang: "Construction of a recombinant human FGF1 expression vector for mammary gland-specific expression in human breast cancer cells." in: Molecular and cellular biochemistry, Vol. 354, Issue 1-2, pp. 39-46, (2011) (PubMed).

Gu, Zhang, Wu, Xu, Cui, Yang, Zhao, Sun: "Differential expression of decorin, EGFR and cyclin D1 during mammary gland carcinogenesis in TA2 mice with spontaneous breast cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 29, pp. 6, (2010) (PubMed).

Details zu FGF1

Target: FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

Andere Bezeichnung: FGF1 (FGF1 Produkte)

Synonyme: AFGF antikoerper, ECGF antikoerper, ECGF-beta antikoerper, ECGFA antikoerper, ECGFB antikoerper, FGF-1 antikoerper, FGF-alpha antikoerper, FGFA antikoerper, GLIO703 antikoerper, HBGF-1 antikoerper, HBGF1 antikoerper, Fgf1 antikoerper, FGF1 antikoerper, aFGF antikoerper, ecgf antikoerper, fgfa antikoerper, ecgfa antikoerper, ecgfb antikoerper, fgf-1 antikoerper, hbgf1 antikoerper, glio703 antikoerper, ecgf-beta antikoerper, fgf-alpha antikoerper, Dffrx antikoerper, Fam antikoerper, Fgf-1 antikoerper, Fgfa antikoerper, zgc:136885 antikoerper, LOC100221393 antikoerper, fgf1 antikoerper, zgc:73249 antikoerper, fibroblast growth factor 1 antikoerper, fibroblast growth factor 1 L homeolog antikoerper, fibroblast growth factor 1b antikoerper, fibroblast growth factor 1a antikoerper, FGF1 antikoerper, fgf1.L antikoerper, fgf1 antikoerper, Fgf1 antikoerper, fgf1b antikoerper, LOC100221393 antikoerper, fgf1a antikoerper

Hintergrund: Fibroblast growth factor 1 (acidic), also known as FGF1/ECGF/HBGF1, is a human gene which is mapped to 5q31. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. Acidic fibroblast growth factor is derived from beta-endothelial cell growth factor (ECGFB) by posttranslational processing. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor.

Synonyms: Acidic fibroblast growth factor antibody|AFGF antibody|Beta endothelial cell growth factor antibody|Beta-endothelial cell growth factor antibody|ECGF antibody|ECGF beta antibody|ECGF-beta antibody|ECGFA antibody|ECGFB antibody|Endothelial cell growth factor alpha antibody|Endothelial cell growth factor alpha antibody|Endothelial Cell Growth Factor beta antibody|FGF 1 antibody|FGF alpha antibody|Fgf1 antibody|FGF1_HUMAN antibody|FGFA antibody|Fibroblast Growth Factor 1 Acidic antibody|Fibroblast growth factor 1 antibody|GLIO703 antibody|HBGF 1 antibody|HBGF-1 antibody|HBGF1 antibody|Heparin binding growth factor 1 antibody|Heparin binding growth factor 1 precursor antibody|Heparin-binding growth factor 1 antibody

Gen-ID: 2246

UniProt: P05230

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung