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EPH Receptor B1 Antikörper (N-Term)

Dieses Anti-EPH Receptor B1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von EPH Receptor B1 in WB, IHC und FACS. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN3042375

Kurzübersicht für EPH Receptor B1 Antikörper (N-Term) (ABIN3042375)

Target

Alle EPH Receptor B1 (EPHB1) Antikörper anzeigen
EPH Receptor B1 (EPHB1)

Reaktivität

  • 50
  • 47
  • 37
  • 1
Human, Maus, Ratte

Wirt

  • 63
  • 4
  • 2
Kaninchen

Klonalität

  • 66
  • 3
Polyklonal

Konjugat

  • 28
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser EPH Receptor B1 Antikörper ist unkonjugiert

Applikation

  • 61
  • 26
  • 26
  • 25
  • 13
  • 10
  • 6
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 15
    • 15
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 56-88, N-Term

    Verwendungszweck

    Anti-Eph receptor B1/EPHB1 Antibody Picoband®

    Sequenz

    RTYQVCNVFE PNQNNWLLTT FINRRGAHRI YTE

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Eph receptor B1/EPHB1 Antibody Picoband® (ABIN3042375). Tested in Flow Cytometry, IHC WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the N-terminus of human Eph receptor B1 , identical to the related mouse and rat sequences.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. "Entrez Gene: EPHB1 EPH receptor B1". 2. Flanagan JG, Vanderhaeghen P (1998). "The ephrins and Eph receptors in neural development". Annu. Rev. Neurosci. 21: 309-45. 3. Tang XX, Biegel JA, Nycum LM, Yoshioka A, Brodeur GM, Pleasure DE, Ikegaki N (Aug 1996). "cDNA cloning, molecular characterization, and chromosomal localization of NET(EPHT2), a human EPH-related receptor protein-tyrosine kinase gene preferentially expressed in brain".Genomics 29 (2): 426-37.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    EPH Receptor B1 (EPHB1)

    Andere Bezeichnung

    EPHB1

    Hintergrund

    Synonyms: Ephrin type-B receptor 1,2.7.10.1,ELK,EPH tyrosine kinase 2,EPH-like kinase 6,EK6,hEK6,Neuronally-expressed EPH-related tyrosine kinase,NET,Tyrosine-protein kinase receptor EPH-2,EPHB1,ELK, EPHT2, HEK6, NET,

    Tissue Specificity: Preferentially expressed in brain.

    Background: Ephrin type-B receptor 1 is a protein that in humans is encoded by the EPHB1 gene. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.

    Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.

    Molekulargewicht

    120 kDa

    Gen-ID

    2047

    UniProt

    P54762

    Pathways

    RTK Signalweg
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