CYR61 Antikörper (AA 54-381)

Produktnummer ABIN3042351

Produktdetails anti-CYR61 Antikörper

Target: CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Bindungsspezifität: AA 54-381

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYR61 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Protein CYR61(CYR61) detection. Tested with WB in Human,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Protein CYR61(CYR61) detection. Tested with WB in Human,Rat.
Gene Name: cysteine-rich, angiogenic inducer, 61
Protein Name: Protein CYR61

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human CCN1 recombinant protein (Position: K54-D381). Human CCN1 shares 91.8% and 92.1% amino acid (aa) sequence identity with mouse and rat CCN1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu CYR61

Target: CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Andere Bezeichnung: CYR61 (CYR61 Produkte)

Hintergrund: Cysteine-rich angiogenic inducer 61 (CYR61) or CCN family member 1 (CCN1), is a matricellular protein that in humans is encoded by the CYR61 gene. CYR61 is a secreted, extracellular matrix (ECM)-associated signaling protein of the CCN family (CCN intercellular signaling protein). And it is capable of regulating a broad range of cellular activities, including cell adhesion, migration, proliferation, differentiation, apoptosis, and senescence through interaction with cell surface integrin receptors and heparan sulfate proteoglycans. During embryonic development, CYR61 is critical for cardiac septal morphogenesis, blood vessel formation in placenta, and vascular integrity. In adulthood CYR61 plays important roles in inflammation and tissue repair, and is associated with diseases related to chronic inflammation, including rheumatoid arthritis, atherosclerosis, diabetes-related nephropathy and retinopathy, and many different forms of cancers.

Synonyms: 3CH61 antibody|CCN 1 antibody|CCN family member 1 antibody|CCN1 antibody|CCN1 antibody|CYR 61 antibody|Cyr61 antibody|CYR61 protein antibody|CYR61 protein precursor antibody|CYR61 protein precursor antibody|CYR61_HUMAN antibody|Cysteine rich angiogenic inducer 61 antibody|Cysteine rich angiogenic inducer 61 antibody|Cysteine rich angiogenic inducer 61 antibody|Cysteine rich heparin binding protein 61 antibody|Cysteine-rich angiogenic inducer 61 antibody|GIG 1 antibody|GIG1 antibody|GIG1 protein antibody|GIG1 protein antibody|IBP-10 antibody|IGF-binding protein 10 antibody|Igfbp 10 antibody|IGFBP-10 antibody|IGFBP10 antibody|IGFBP10 antibody|Insulin like growth factor binding protein 10 antibody|Insulin like growth factor binding protein 10 antibody|Insulin like growth factor binding protein 10 antibody|Insulin-like growth factor-binding protein 10 antibody|Protein CYR61 antibody|Protein GIG1 antibody

Gen-ID: 3491

UniProt: O00622

Pathways: Positive Regulation of Endopeptidase Activity, Growth Factor Binding