TUBA1B Antikörper (AA 427-441)
Kurzübersicht für TUBA1B Antikörper (AA 427-441) (ABIN303379)
Target
Alle TUBA1B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 427-441
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Spezifität
- This antibody makes an excellent Loading Control.
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Aufreinigung
- Immunoaffinity Chromatography.
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Immunogen
- Synthetic peptide corresponding to Amino acids 427-441 of Human alpha Tubulin.
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Applikationshinweise
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Immunohistochemistry on Paraffin Sections (2.5 μg/mL). Immunofluorescence. Western Blot (1/500-1/3000). ELISA (1/5000-1/25000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid cycles of freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store the antibody (in aliquots) at-20 °C. Dilute only prior to immediate use.
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- TUBA1B (Tubulin, alpha 1B (TUBA1B))
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Andere Bezeichnung
- alpha Tubulin / TUBA1B
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Hintergrund
- Microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Tubulin itself is a globular protein consisting of two polypeptides (alpha and beta tubulin). Alpha and beta tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter. Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase. Detyrosinated alpha tubulin is referred to as Glu-tubulin. Another post-translational modification of detyrosinated alpha tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle.Synonyms: Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-1B chain, Tubulin alpha-ubiquitous chain
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Gen-ID
- 10376
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NCBI Accession
- NP_006073
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UniProt
- P68363
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Pathways
- Microtubule Dynamics, M Phase
Target
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