SLC22A6 Antikörper (AA 534-550)

Produktnummer ABIN3032684

Der Kaninchen Polyklonal Anti-SLC22A6-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, SLC22A6 in Proben von Human und Ratte zu detektieren.

Kurzübersicht für SLC22A6 Antikörper (AA 534-550) (ABIN3032684)

Target: SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC22A6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SLC22A6 Antikörper

Bindungsspezifität: AA 534-550

Aufreinigung: Antigen affinity

Immunogen: Amino acids 534-550 (QKYMVPLQASAQEKNGL-human) were used as the immunogen for this SLC22A6 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the SLC22A6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the SLC22A6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu SLC22A6

Target: SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))

Andere Bezeichnung: SLC22A6

Hintergrund: Solute carrier family 22 (organic anion transporter), member 6, also called OAT1 or PAHT, is a protein that in humans is encoded by the SLC22A6 gene, which is also a member of the organic anion transporter (OAT) family of proteins. It is a transmembrane protein that is expressed in the brain, the placenta, the eyes, smooth muscles, and the basolateral membrane of proximal tubular cells of the kidneys. It plays a central role in renal organic anion transport. Along with OAT3, OAT1/SLC22A6 mediates the uptake of a wide range of relatively small and hydrophilic organic anions from plasma into the cytoplasm of the proximal tubular cells of the kidneys. The protein functions as organic anion exchanger. When the uptake of one molecule of an organic anion is transported into a cell by an SLC22A6 exchanger, one molecule of an endogenous dicarboxylic acid(such as glutarate, ketoglutarate, etc) is simultaneously transported out of the cell.

UniProt: Q4U2R8

Pathways: Dicarboxylic Acid Transport