Progesterone Receptor Antikörper (AA 595-933)

Produktnummer ABIN3032309

Der Kaninchen Polyklonal Anti-Progesterone Receptor-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, Progesterone Receptor in Proben von Human und Ratte zu detektieren.

Kurzübersicht für Progesterone Receptor Antikörper (AA 595-933) (ABIN3032309)

Target: Progesterone Receptor (PGR)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Progesterone Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Progesterone Receptor Antikörper

Bindungsspezifität: AA 595-933

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 595-933) was used as the immunogen for this Progesterone Receptor antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Progesterone Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Progesterone Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Progesterone Receptor

Target: Progesterone Receptor (PGR)

Andere Bezeichnung: Progesterone Receptor

Hintergrund: The progesterone receptor (PR) is an intracellular steroid receptor that specially binds progesterone in humans. It is encoded by a single PGR gene residing on chromosome 11q22. The PR gene uses separate promoters and translational start sites to produce 2 isoforms, PRA and PRB, which are identical except for an additional 165 amino acids present only in the N terminus of PRB. It can be observed in human breast tissues. The proteins function as dimeric molecules in nuclei to regulate the transcription of target genes in a ligand-responsive manner.

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration