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DREAM Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-DREAM-Antikörper wurde für WB validiert. Er ist geeignet, DREAM in Proben von Human zu detektieren.
Produktnummer ABIN3031577

Kurzübersicht für DREAM Antikörper (N-Term) (ABIN3031577)

Target

Alle DREAM (KCNIP3) Antikörper anzeigen
DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Reaktivität

  • 51
  • 31
  • 30
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Human

Wirt

  • 47
  • 12
  • 2
Kaninchen

Klonalität

  • 52
  • 9
Polyklonal

Konjugat

  • 34
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DREAM Antikörper ist unkonjugiert

Applikation

  • 52
  • 27
  • 23
  • 13
  • 9
  • 8
  • 6
  • 6
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 13
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Aufreinigung

    Antigen affinity

    Immunogen

    An amino acid sequence from the N-terminus of human Calsenilin (MQPAKEVTKASDGSLL) was used as the immunogen for this CSEN antibody.

    Isotyp

    IgG
  • Applikationshinweise

    The stated application concentrations are suggested starting amounts. Titration of the CSEN antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    Lagerung

    -20 °C

    Informationen zur Lagerung

    After reconstitution, the CSEN antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target

    DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

    Andere Bezeichnung

    CSEN

    Hintergrund

    Calsenilin (CSEN) is a calcium-dependent transcriptional repressor that is highly expressed in central nervous system, thyroid gland, testis, thymus, and immune cells. The KCNIP3 gene encodes a member of the family of voltage-gated potassium(Kv) channel-interacting proteins, which belong to the neuronal calcium sensor family of proteins. Calsenilin functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. KCNIP3-regulated genes have a critical function in Ig subclass production and proliferation in B lymphocytes. It has been shown to interact with PSEN1 and PSEN2.

    UniProt

    Q9Y2W7
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