PNKP Antikörper (Internal Region)

Produktnummer ABIN303129

Produktdetails anti-PNKP Antikörper

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PNKP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: ,Species:Human, Dog, Mouse and Rat.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to an internal region of human PNK protein.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Sections (5 μg/mL). Immunofluorescence. Western Blot (1/300-1/1500). ELISA (1/3000-1/12000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at-20 °C. Dilute only prior to immediate use.

Details zu PNKP

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Andere Bezeichnung: PNKP (PNKP Produkte)

Synonyme: EIEE10 antikoerper, MCSZ antikoerper, PNK antikoerper, Tb06.28P18.320 antikoerper, 21.m03011 antikoerper, 1810009G08Rik antikoerper, polynucleotide kinase 3'-phosphatase antikoerper, hypothetical protein antikoerper, polynucleotide kinase 3'- phosphatase antikoerper, PNKP antikoerper, Pnkp antikoerper, Tc00.1047053507017.50 antikoerper, Tc00.1047053505807.190 antikoerper, Tb927.6.1580 antikoerper, BBOV_IV000690 antikoerper, CC1G_05202 antikoerper, PGTG_20262 antikoerper, PGTG_18987 antikoerper, pnkp.S antikoerper, pnkp antikoerper

Hintergrund: Mammalian PNK (also known as PNKP, Polynucleotide kinase 3'-phosphatase, DNA 5'-kinase/3'-phosphatase and Polynucleotide kinase) catalyzes the 5 phosphorylation of nucleic acids and can have associated 3 phosphatase activity, predictive of an important function in DNA repair following ionizing radiation or oxidative damage. PNK is a nuclear protein that is expressed in many tissues with highest expression in spleen and testis, and lowest expression in small intestine.Synonyms: Bifunctional polynucleotide phosphatase/kinase, DNA 5'-kinase/3'-phosphatase, Polynucleotide kinase-3'-phosphatase

Gen-ID: 11284

NCBI Accession: NP_009185

UniProt: Q96T60

Pathways: DNA Reparatur, Nucleotide Phosphorylation