PNKP Antikörper (Internal Region)

Produktnummer ABIN303129

Der Kaninchen Polyklonal anti-PNKP Antikörper (ABIN303129) detektiert spezifisch PNKP in WB, IF, IHC (p) und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte und Hund.

Kurzübersicht für PNKP Antikörper (Internal Region) (ABIN303129)

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PNKP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-PNKP Antikörper

Bindungsspezifität: Internal Region

Spezifität: ,Species:Human, Dog, Mouse and Rat.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide corresponding to an internal region of human PNK protein.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Sections (5 μg/mL). Immunofluorescence. Western Blot (1/300-1/1500). ELISA (1/3000-1/12000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at-20 °C. Dilute only prior to immediate use.

Details zu PNKP

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Andere Bezeichnung: PNKP

Hintergrund: Mammalian PNK (also known as PNKP, Polynucleotide kinase 3'-phosphatase, DNA 5'-kinase/3'-phosphatase and Polynucleotide kinase) catalyzes the 5 phosphorylation of nucleic acids and can have associated 3 phosphatase activity, predictive of an important function in DNA repair following ionizing radiation or oxidative damage. PNK is a nuclear protein that is expressed in many tissues with highest expression in spleen and testis, and lowest expression in small intestine.Synonyms: Bifunctional polynucleotide phosphatase/kinase, DNA 5'-kinase/3'-phosphatase, Polynucleotide kinase-3'-phosphatase

Gen-ID: 11284

NCBI Accession: NP_009185

UniProt: Q96T60

Pathways: DNA Reparatur, Nucleotide Phosphorylation