EPO Antikörper (AA 1-166)

Produktnummer ABIN3030866

Produktdetails anti-EPO Antikörper

Target: EPO (Erythropoietin (EPO))

Bindungsspezifität: AA 1-166

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPO Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA (Standard)

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 1-166) was used as the immunogen for this EPO antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the EPO antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot (recombinant protein): 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,ELISA: 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the EPO antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu EPO

Target: EPO (Erythropoietin (EPO))

Andere Bezeichnung: EPO (EPO Produkte)

Substanzklasse: Hormone

Hintergrund: EPO, Erythropoietin, is an acidic glycoprotein hormone with a molecular mass of 34 kD. It is a cytokine for erythrocyte (red blood cell) precursors in the bone marrow. This gene is mapped to 7q22.1. It is produced by interstitial fibroblasts in the kidney in close association with peritubular capillary and tubular epithelial cells. It is also produced in perisinusoidal cells in the liver. While liver production predominates in the fetal and perinatal period, renal production is predominant during adulthood. As the prime regulator of red cell production, its major functions are to promote erythroid differentiation and to initiate hemoglobin synthesis. It also has other known biological functions. For example, erythropoietin plays an important role in the brains response to neuronal injury. EPO is also involved in the wound healing process.

UniProt: P01588

Pathways: JAK-STAT Signalweg, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity