CEBPB Antikörper (AA 1-200)

Produktnummer ABIN3030344

Der Kaninchen Polyklonal Anti-CEBPB-Antikörper wurde für WB, IHC (p) und IHC (fro) validiert. Er ist geeignet, CEBPB in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für CEBPB Antikörper (AA 1-200) (ABIN3030344)

Target: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEBPB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-CEBPB Antikörper

Bindungsspezifität: AA 1-200

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 1-200) was used as the immunogen for this C/EBP beta antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the C/EBP beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the C/EBP beta antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu CEBPB

Target: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Andere Bezeichnung: C/EBP beta

Hintergrund: CCAAT/enhancer-binding protein beta, also known as is C/EBP beta, is a protein that in humans is encoded by the CEBPB gene. The protein encoded by this intronless gene is a bZIP transcription factor that can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the< a href=../search_result.php?search_txt=il-6>IL-6gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. C/EBP beta is critical for normal macrophage functioning, an important immune cell sub-type. Observational work has shown that expression of C/EBP beta in blood leukocytes is positively associated with muscle strength in humans, emphasizing the importance of the immune system, and particularly macrophages, in the maintenance of muscle function.

Gen-ID: 1051

Pathways: Interferon-gamma Pathway, Autophagie, Brown Fat Cell Differentiation