Caspase 7 Antikörper (AA 237-255)

Produktnummer ABIN3030315

Dieses Anti-Caspase 7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Caspase 7 in WB und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für Caspase 7 Antikörper (AA 237-255) (ABIN3030315)

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Caspase 7 Antikörper

Bindungsspezifität: AA 237-255

Aufreinigung: Antigen affinity

Immunogen: Amino acids 237-255 (RGSWFVQALCSILEEHGKD-human) were used as the immunogen for this Caspase-7 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the Caspase-7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Caspase-7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Caspase 7

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Andere Bezeichnung: Caspase-7

Hintergrund: Caspase-7 is a human protein encoded by the CASP7 gene. Orthologs have been identified in nearly all mammals for which complete genome data are available. CASP7 is a member of the cysteine aspartate protease family of proteins, and has been shown to be an executioner protein of apoptosis. Using radiation hybrid mapping, the CASP7 gene was localized to human chromosome 10q25.1-q25.2. The orderly activation of the protein regulates microglia activation through a protein kinase C-delta (PRKCD)-dependent pathway.

UniProt: P55210

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity