Caspase 4 Antikörper (AA 104-124)

Produktnummer ABIN3030308

Der Kaninchen Polyklonal anti-Caspase 4 Antikörper wird verwendet zum Nachweis von Caspase 4 in Proben von Human. Er wurde validiert für WB und IHC (p).

Kurzübersicht für Caspase 4 Antikörper (AA 104-124) (ABIN3030308)

Target: Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Caspase 4 Antikörper

Bindungsspezifität: AA 104-124

Aufreinigung: Antigen affinity

Immunogen: Amino acids 104-124 (DALKLCPHEEFLRLCKERAEE-human) were used as the immunogen for this Caspase-4 antibody. This sequence is from the large subunit.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the Caspase-4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Caspase-4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Caspase 4

Target: Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

Andere Bezeichnung: Caspase-4

Hintergrund: Caspase-4 is an enzyme that proteolytically cleaves other proteins at an aspartic acid residue, and belongs to a family of cysteine proteases called caspases. The CASP4 gene is mapped to a P1 clone containing the ICE gene, which is located at chromosome 11q22.2-q22.3. It contains 8 coding exons. The function of Caspase-4 is not fully known, but it is believed to be an inflammatory caspase, along with CASP1, CASP5 and the murine homolog CASP11, with a role in the immune system.

UniProt: P49662

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity