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BUB3 Antikörper (Middle Region)

BUB3 Reaktivität: Human, Maus, Ratte WB, IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3030213
  • Target Alle BUB3 Antikörper anzeigen
    BUB3 (Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))
    Bindungsspezifität
    • 15
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 50
    • 37
    • 32
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 63
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 56
    • 11
    Polyklonal
    Konjugat
    • 35
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BUB3 Antikörper ist unkonjugiert
    Applikation
    • 47
    • 18
    • 17
    • 14
    • 14
    • 14
    • 12
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Aufreinigung
    Antigen affinity
    Immunogen
    An amino acid sequence from the middle region of human Bub3 (DHQLKMHDLNTDQEN) was used as the immunogen for this Bub3 antibody (100% homologous in human, mouse and rat).
    Isotyp
    IgG
    Top Product
    Discover our top product BUB3 Primärantikörper
  • Applikationshinweise
    The stated application concentrations are suggested starting amounts. Titration of the Bub3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Lagerung
    -20 °C
    Informationen zur Lagerung
    After reconstitution, the Bub3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    BUB3 (Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))
    Andere Bezeichnung
    Bub3 (BUB3 Produkte)
    Synonyme
    BUB3L antikoerper, hBUB3 antikoerper, Aa2-050 antikoerper, xbub3 antikoerper, AU019800 antikoerper, AU021329 antikoerper, AU043350 antikoerper, AW146323 antikoerper, C78067 antikoerper, BUB3, mitotic checkpoint protein antikoerper, BUB3 mitotic checkpoint protein antikoerper, BUB3 mitotic checkpoint protein L homeolog antikoerper, BUB3 antikoerper, Bub3 antikoerper, bub3.L antikoerper
    Hintergrund
    Budding uninhibited by benzimidazoles 3 is a protein that in humans is encoded by the BUB3 gene. It is a protein involved with the regulation of the Spindle Assembly Checkpoint (SAC), though Bub3 is non-essential in yeast, it is essential in higher eukaryotes. As one of the checkpoint proteins, it delays the irreversible onset of anaphase through direction of kinetochore localization during prometaphase to achieve biorentation. Bub3 directs the localization of Bub1 at the kinetochore in order to activate the SAC. It also acts as a regulator in that it affects binding of Mad3 to Mad2.
    UniProt
    O43684
    Pathways
    Maintenance of Protein Location
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