Aurora Kinase C Antikörper (C-Term)

Produktnummer ABIN3030080

Der Kaninchen Polyklonal Anti-Aurora Kinase C-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, Aurora Kinase C in Proben von Human zu detektieren.

Kurzübersicht für Aurora Kinase C Antikörper (C-Term) (ABIN3030080)

Target: Aurora Kinase C (AURKC)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aurora Kinase C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-Aurora Kinase C Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Purified

Immunogen: A portion of the C-terminal region of the human protein was used as immunogen for this AURKC antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the AURKC antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the AURKC antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu Aurora Kinase C

Target: Aurora Kinase C (AURKC)

Andere Bezeichnung: AURKC

Hintergrund: Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.

UniProt: Q9UQB9

Pathways: Zellzyklus, Maintenance of Protein Location