Angiostatin Antikörper (AA 103-352)

Produktnummer ABIN3028464

Der Kaninchen Polyklonal anti-Angiostatin Antikörper (ABIN3028464) detektiert spezifisch Angiostatin in WB, ELISA und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Angiostatin Antikörper (AA 103-352) (ABIN3028464)

Target: Angiostatin (ANG)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Angiostatin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Angiostatin Antikörper

Bindungsspezifität: AA 103-352

Verwendungszweck: Angiostatin K1-3 Antibody

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 103-352) was used as the immunogen for this Angiostatin K1-3 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Angiostatin K1-3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Angiostatin K1-3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Angiostatin

Target: Angiostatin (ANG)

Andere Bezeichnung: Angiostatin K1-3

Hintergrund: Ang K1-3 is a proteolytic fragment of Plasminogen. It is a single, non-glycosylated polypeptide chain containing 259 amino acids. It represents a proteolytic fragment of plasminogen containing the first three kringle structures. Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth. It displays increased inhibitory activity (ED50=70nM) relative to kringles 1-4 (ED50 = 135nM).

UniProt: P00747

Pathways: Lipid Metabolism