IL-24 Antikörper (AA 100-150)

Produktnummer ABIN302672

Der Kaninchen Polyklonal Anti-IL-24-Antikörper wurde für WB, IHC (p) und FACS validiert. Er ist geeignet, IL-24 in Proben von Human zu detektieren.

Kurzübersicht für IL-24 Antikörper (AA 100-150) (ABIN302672)

Target: IL-24 (IL24) (Interleukin 24 (IL24))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-24 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-IL-24 Antikörper

Bindungsspezifität: AA 100-150

Spezifität: This antibody recognizes Interleukin 24 (IL24/Mda-7).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Protein G Chromatography

Immunogen: A portion of amino acids 100-150 of human IL-24 was used as the immunogen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry. Western Blot: 0.5-3 μg/mL. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS, 0.05 % Sodium Azide, 0.2 % Gelatin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C to -70 °C for longer.

Details zu IL-24

Target: IL-24 (IL24) (Interleukin 24 (IL24))

Andere Bezeichnung: Interleukin-24 / IL24

Hintergrund: Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.Synonyms: IL-24, MDA7, Melanoma differentiation-associated gene 7 protein, ST16, Suppression of tumorigenicity 16 protein

Gen-ID: 11009

NCBI Accession: NP_001172085

UniProt: Q13007

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagie