HLA-DR Antikörper

Produktnummer ABIN3026340

Der Maus Monoklonal anti-HLA-DR Antikörper wird verwendet zum Nachweis von HLA-DR in Proben von Human, Cat und Rind (Kuh). Er wurde validiert für FACS und IF.

Kurzübersicht für HLA-DR Antikörper (ABIN3026340)

Target: HLA-DR

Reaktivität: Human, Cat, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HLA-DR Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: 169-1B5-2

Produktdetails anti-HLA-DR Antikörper

Produktmerkmale: This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 Molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.

Aufreinigung: Protein G affinity chromatography

Immunogen: Human peripheral blood leukocytes were used as the immunogen for the HLA-DR antibody.

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the HLA-DR antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the HLA-DR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu HLA-DR

Target: HLA-DR

Andere Bezeichnung: HLA-DR (MHC II)

Hintergrund: This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36  kDa alpha (heavy) chain and a 28  kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 Molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response