HLA-DR Antikörper

Produktnummer ABIN7449537

Der Maus Monoklonal anti-HLA-DR Antikörper (Klon LN3) (ABIN7449537) detektiert spezifisch HLA-DR in FACS, WB, IHC, ICC und IF (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für HLA-DR Antikörper (ABIN7449537)

Target: HLA-DR

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HLA-DR Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Klon: LN3

Produktdetails anti-HLA-DR Antikörper

Verwendungszweck: Mouse anti-HLA-DR Monoclonal Antibody Purified [LN3]

Aufreinigung: Purified

Immunogen: Activated human peripheral blood mononuclear cells

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 17:40:00

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 50 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2 - 8 °C

Haltbarkeit: 12 months

Details zu HLA-DR

Target: HLA-DR

Andere Bezeichnung: HLA-DR

Hintergrund: In humans, Major Histocompatibility Locus (MHC) class II molecules are encoded by three different loci, HLA-DR, -DQ, and -DP, which display ~70 % similarity to each other. Polymorphism is a notable feature of MHC class II genes. HLA-DR, HLA-DP, and HLA-DQ are heterodimeric cell surface glycoproteins comprised of an α (heavy) chain and a β (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 Molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. Variations in the HLA gene expression are crucial to graft survival.

Gen-ID: 3122

UniProt: P01903

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response