MYB Antikörper (AA 119-135)

Produktnummer ABIN3026199

Der Maus Monoklonal anti-MYB Antikörper wird verwendet zum Nachweis von MYB in Proben von Human. Er wurde validiert für ELISA.

Kurzübersicht für MYB Antikörper (AA 119-135) (ABIN3026199)

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MYB Antikörper ist unkonjugiert

Applikation: ELISA

Klon: MYB286

Produktdetails anti-MYB Antikörper

Bindungsspezifität: AA 119-135

Verwendungszweck: c-Myb Antibody

Sequenz: RRKVEQEGYP QESSKAG

Aufreinigung: Protein G affinity chromatography

Immunogen: Amino acids 119-135 (RRKVEQEGYPQESSKAG) from the human protein were used as the immunogen for this c-Myb antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: The optimal dilution of the c-Myb antibody for each application should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the c-Myb antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu MYB

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Andere Bezeichnung: c-Myb

Hintergrund: The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.

UniProt: P01104

Pathways: Chromatin Binding, Positive Regulation of Immune Effector Process