Liver Arginase Antikörper (AA 1-150)
Kurzübersicht für Liver Arginase Antikörper (AA 1-150) (ABIN3025824)
Target
Alle Liver Arginase (ARG1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- AA 1-150
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Verwendungszweck
- Arginase 1 Antibody (azide and preservative free)
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- A recombinant fragment from amino acids 1-150 of human ARG1 was used as the immunogen for the Arginase 1 antibody.
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Isotyp
- IgG3, kappa
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Applikationshinweise
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Optimal dilution of the Arginase 1 antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the Arginase 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
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Andere Bezeichnung
- Arginase 1
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Hintergrund
- Recognizes a protein of 35-38 kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.
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UniProt
- P05089
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Pathways
- Cellular Response to Molecule of Bacterial Origin
Target
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