BCL2L1 Antikörper (AA 3-14)

Produktnummer ABIN3025808

Dieser Maus Monoklonal Antikörper detektiert spezifisch BCL2L1 in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für BCL2L1 Antikörper (AA 3-14) (ABIN3025808)

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BCL2L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: BX006-2H12

Produktdetails anti-BCL2L1 Antikörper

Bindungsspezifität: AA 3-14

Verwendungszweck: Bcl-X Antibody Cocktail (azide and preservative free)

Sequenz: QSNRELVVDF LS

Aufreinigung: Protein G affinity chromatography

Immunogen: Amino acids 3-14 (QSNRELVVDFLS) from the human protein were used as the immunogen for this Bcl-X antibody.

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: The optimal dilution of the Bcl-X antibody for each application should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Bcl-X antibody cocktail at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu BCL2L1

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Andere Bezeichnung: Bcl-X

Hintergrund: Recognizes a protein of 27 kDa, identified as the Bcl-X protein. This mAb cocktail shows no cross-reaction with Bcl-2 or Bax protein. Bcl-X has two isoforms, Bcl-XL (long), a 241 amino acid protein which suppresses cell death. And Bcl-XS (short), a 178 amino acid protein lacking a 63 amino acid domain which functions as a dominant inhibitor of Bcl-2. This mAb reacts with both Bcl-XS and Bcl-XL proteins.

UniProt: Q07817

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling