CD22 Antikörper

Produktnummer ABIN3025757

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD22 in FACS, IF und Func. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für CD22 Antikörper (ABIN3025757)

Target: CD22 (CD22 Molecule (CD22))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD22 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Klon: MYG13

Produktdetails anti-CD22 Antikörper

Aufreinigung: Protein G affinity chromatography

Immunogen: Human Raji cells were used as the immunogen for the CD22 antibody.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CD22 antibody should be determined by the researcher.\. Functional Activity (Order SAF formulation),Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the CD22 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu CD22

Target: CD22 (CD22 Molecule (CD22))

Andere Bezeichnung: CD22

Hintergrund: Recognizes a protein of 130-140  kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.