VCAM1 Antikörper

Produktnummer ABIN3025722

Der Maus Monoklonal Anti-VCAM1-Antikörper wurde für FACS, IF und BP validiert. Er ist geeignet, VCAM1 in Proben von Human zu detektieren.

Kurzübersicht für VCAM1 Antikörper (ABIN3025722)

Target: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser VCAM1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Blocking Peptide (BP)

Klon: B-K9

Produktdetails anti-VCAM1 Antikörper

Aufreinigung: Protein G affinity chromatography

Immunogen: Activated human umbilical vein endothelial cells (HUVEC) were used as the immunogen for the VCAM1 antibody.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the VCAM1 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 1-2 μg/mL, Functional blocking: order BSA/azide free format

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the VCAM1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu VCAM1

Target: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Andere Bezeichnung: VCAM1

Hintergrund: Recognizes a protein of 110  kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1), L1CAM and INCAM-100). It is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. L1CAM serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This mAb inhibits the binding of leukocytes to L1CAM on stimulated endothelial cells.

Pathways: Carbohydrate Homeostasis