Rekombinanter Nkx2-2 Antikörper

Produktnummer ABIN3025346

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch Nkx2-2 in IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter Nkx2-2 Antikörper (ABIN3025346)

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Nkx2-2 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RMNK2-1

Produktdetails anti-Nkx2-2 Antikörper

Aufreinigung: Protein A affinity chromatography

Immunogen: A human partial recombinant protein was used as the immunogen for this rabbit monoclonal NKX2.2 antibody.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: Titering of the NKX2.2 antibody may be required for optimal performance.

1. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10  mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.\. IF: 0.5-1 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the NKX2.2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu Nkx2-2

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Andere Bezeichnung: NKX2.2

Hintergrund: NKX2.2 acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter (By similarity). [UniProt]

Gen-ID: 4821

Pathways: Dopaminergic Neurogenesis