BAI1 Antikörper (N-Term)

Produktnummer ABIN302508

Dieses Anti-BAI1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BAI1 in IHC (p). Geeignet für Human und Maus.

Kurzübersicht für BAI1 Antikörper (N-Term) (ABIN302508)

Target: BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAI1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-BAI1 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects Brain-Specific Angiogenesis Inhibitor 1 (BAI1) at N-terminal domain.

Aufreinigung: Immunoaffinity chromatography

Immunogen: BAI1 antibody was raised against synthetic peptide from N-terminal domain of human BAI1.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin sections (20 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.7 mg/mL

Buffer: PBS containing 0.09 % sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Details zu BAI1

Target: BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))

Andere Bezeichnung: BAI1

Hintergrund: BAI1 is an Orphan-B GPCR with an unknown ligand. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis, and a growth suppressor of glioblastoma. Along with BAI1, there are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3, which have similar tissue specificities and structures. However, only BAI1 is transcriptionally regulated by p53. Loss of BAI1 expression has been implicated in glioblastoma.Synonyms: BAI-1, Brain-specific angiogenesis inhibitor 1

Gen-ID: 575

NCBI Accession: NP_001693

UniProt: O14514

Pathways: p53 Signalweg