CD70 Antikörper

Produktnummer ABIN3024471

Der Maus Monoklonal Anti-CD70-Antikörper wurde für ELISA, FACS, IP, IF, IHC (fro) und InhA validiert. Er ist geeignet, CD70 in Proben von Human zu detektieren.

Kurzübersicht für CD70 Antikörper (ABIN3024471)

Target: CD70 (CD70 Molecule (CD70))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD70 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Inhibition Assay (InhA)

Klon: BU69

Produktdetails anti-CD70 Antikörper

Aufreinigung: Protein G affinity chromatography

Immunogen: The human WM-1 (Waldenstrom s macroglobulinemia) cell line was used as the immunogen for the CD70 antibody.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CD70 antibody should be determined by the researcher.

1. This mAb blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells.\. ELISA (order Ab without BSA),Functional Activity: Inhibits T cell proliferation induced by dendritic cells (Order SAF formulation) (1),Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Immunoprecipitation: 0.5-1 μg/500 μg protein lysate,Immunohistochemistry (Frozen): 0.5-1 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the CD70 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu CD70

Target: CD70 (CD70 Molecule (CD70))

Andere Bezeichnung: CD70

Hintergrund: CD70 belongs to the tumor necrosis factor (TNF) ligand family. It is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.

Pathways: Cancer Immune Checkpoints