GPR68 Antikörper (N-Term)

Produktnummer ABIN302446

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GPR68 in IHC (p). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für GPR68 Antikörper (N-Term) (ABIN302446)

Target: GPR68 (G Protein-Coupled Receptor 68 (GPR68))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR68 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GPR68 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects OGR1 / GPR68 at N-term.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse (others see 'Immunogen Remarks')Species reactivity (tested):Human

Aufreinigung: Immunoaffinity chromatography

Immunogen: Synthetic 17 amino acid peptide from N-terminal domain of human GPR68 / OGR1

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin sections (20 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -80 °C for longer.

Details zu GPR68

Target: GPR68 (G Protein-Coupled Receptor 68 (GPR68))

Andere Bezeichnung: GPR68 / OGR1

Hintergrund: OGR1, a Lysophospholipid/Lysosphingolipid Receptor, was isolated by degenerate PCR from an ovarian cell line cDNA library. It is not expressed in normal ovary. OGR1 binds sphingosylphosporylcholine, a lipid molecule involved in cell growth and survival. Recently, OGR1 has been shown to act as a proton-sensing receptor stimulating inositol phosphate formation (Ludwig et al. 2003).Synonyms: G-protein coupled receptor 68, GPR12A, Ovarian cancer G-protein coupled receptor 1, Sphingosylphosphorylcholine receptor

Gen-ID: 8111

NCBI Accession: NP_001171147

UniProt: Q15743